Immunization Project, Pan American Health Organization, Washington, DC, USA.
Vaccine. 2011 Jan 29;29(5):1099-106. doi: 10.1016/j.vaccine.2010.11.075. Epub 2010 Dec 7.
Rotavirus, pneumococcal conjugate and HPV vaccines have the potential to make substantial gains in health, specifically in reducing child mortality and improving women's health. Decisions regarding new vaccine introduction should be grounded in a broad evidence base that reflects national conditions. In this paper, we describe the Pan American Health Organization ProVac Initiative's experience in strengthening national decision making regarding new vaccine introduction through five sets of activities: (1) strengthening infrastructure for decision making; (2) developing tools for economic analyses and providing training to national multidisciplinary teams; (3) collecting data, conducting analysis, and gathering a framework of evidence; (4) advocating for evidence-based decisions; and (5) effectively planning for new vaccine introduction when evidence supports it. Key lessons learned regarding the role of multidisciplinary country teams, provision of direct technical support, development of tools, and provision of distance and in-person training are highlighted.
轮状病毒、肺炎球菌结合疫苗和 HPV 疫苗有可能在健康方面取得重大进展，特别是在降低儿童死亡率和改善妇女健康方面。有关新疫苗引入的决策应基于广泛的反映国家情况的证据基础。本文描述了泛美卫生组织 ProVac 倡议通过以下五组活动加强国家新疫苗引入决策的经验：（1）加强决策的基础设施；（2）开发经济分析工具并为国家多学科团队提供培训；（3）收集数据、进行分析并建立证据框架；（4）倡导基于证据的决策；（5）在有证据支持的情况下，有效地规划新疫苗的引入。重点介绍了关于多学科国家团队的作用、提供直接技术支持、开发工具以及提供远程和现场培训的关键经验教训。
