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自身免疫性疾病累及唾液腺的内镜治疗

Endoscopic treatment of salivary glands affected by autoimmune diseases.

作者信息

Shacham Rachel, Puterman Max B, Ohana Nili, Nahlieli Oded

机构信息

Department of Oral and Maxillofacial Surgery, Barzilai Medical Center, Ashkelon, Israel.

出版信息

J Oral Maxillofac Surg. 2011 Feb;69(2):476-81. doi: 10.1016/j.joms.2010.10.002. Epub 2010 Dec 8.

Abstract

PURPOSE

To asses the possibility of an endoscopic technique to diagnose, treat, and maintain the salivary glands in patients with Sjögren syndrome and systemic lupus erythematosus.

PATIENTS AND METHODS

A total of 8 patients with Sjögren syndrome and 2 with systemic lupus erythematosus with affected salivary glands were included in the present study. The treatment approach included parotid sialoendoscopy with thorough rinsing, and Stenson's duct dilation using hydrostatic pressure and a high-pressure balloon. Hydrocortisone 100 mg was injected through direct vision into the duct. The study was exempt by the Barzilai Medical Center review board.

RESULTS

The main diagnosis of the patients was chronic recurrent parotitis, with the exception of 1 patient, who presented with salivary stones.

CONCLUSIONS

The pathologic features of the salivary glands resulting from Sjögren syndrome and systemic lupus erythematosus can be managed successfully using an endoscopic approach.

摘要

目的

评估一种内镜技术用于诊断、治疗和维持干燥综合征及系统性红斑狼疮患者唾液腺功能的可能性。

患者与方法

本研究共纳入8例患有干燥综合征且唾液腺受累的患者以及2例患有系统性红斑狼疮且唾液腺受累的患者。治疗方法包括腮腺唾液腺内镜检查及彻底冲洗,以及使用静水压力和高压球囊扩张斯滕森导管。在直视下将100毫克氢化可的松注入导管。本研究获巴尔齐莱医疗中心审查委员会豁免。

结果

除1例患者出现唾液腺结石外,其余患者的主要诊断为慢性复发性腮腺炎。

结论

采用内镜方法可成功处理干燥综合征和系统性红斑狼疮导致的唾液腺病理特征。

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