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阴茎重建术后狭窄的尿道成形术:单机构经验。

Urethroplasty for strictures after phallic reconstruction: a single-institution experience.

机构信息

Department of Urology, Ghent University Hospital, Ghent, Belgium.

出版信息

Eur Urol. 2011 Jul;60(1):150-8. doi: 10.1016/j.eururo.2010.11.015. Epub 2010 Nov 21.

Abstract

BACKGROUND

Treatment recommendations for strictures after phalloplasty are lacking.

OBJECTIVE

Our aim was to evaluate the outcome of urethroplasty for strictures after phalloplasty and to provide treatment recommendations based on this experience.

DESIGN, SETTING, AND PARTICIPANTS: One hundred and eighteen urethroplasties were performed in 79 patients. Mean patient age was 37.6 yr. Mean follow-up was 39 mo.

INTERVENTION

Different types of urethroplasty were used: meatotomy, Heineke-Mikulicz principle (HMP), excision and primary anastomosis (EPA), free graft urethroplasty (FGU), pedicled flap urethroplasty (PFU), two-stage urethroplasty (TSU), and perineostomy followed by urethral reconstruction (PUR).

MEASUREMENTS

Stricture recurrence was defined as the need for additional instrumentation or surgery.

RESULTS AND LIMITATIONS

Mean stricture length was 3.6 cm. Stricture location was at the meatus, phallic urethra, anastomosis, fixed part, and different locations in 18, 28, 48, 15, and 9 urethroplasties, respectively. Stricture recurrence was observed in 44 urethroplasties (41.12%). Stricture recurrence rate for meatotomy, HMP, EPA, FGU, PFU, TSU, and PUR was 25%, 42.11%, 42.86%, 50%, 40%, 30.3%, and 61.9%, respectively.

CONCLUSIONS

The main stricture location after phalloplasty is the anastomosis between the phallic and the fixed part. Urethroplasty for strictures after phalloplasty is associated with a relatively high recurrence rate.

TRIAL REGISTRATION

EC UZG 2007/434.

摘要

背景

阴茎成形术后狭窄的治疗推荐意见尚缺乏。

目的

我们旨在评估阴茎成形术后狭窄行尿道成形术的结果,并基于此经验提供治疗建议。

设计、地点和参与者:79 例患者共行 118 例尿道成形术。患者平均年龄为 37.6 岁。平均随访时间为 39 个月。

干预措施

采用不同类型的尿道成形术:尿道切开术、Heineke-Mikulicz 原则(HMP)、切除和一期吻合术(EPA)、游离移植物尿道成形术(FGU)、带蒂皮瓣尿道成形术(PFU)、两期尿道成形术(TSU)和会阴切开术加尿道重建术(PUR)。

测量

狭窄复发定义为需要额外的器械或手术。

结果和局限性

平均狭窄长度为 3.6cm。狭窄位置分别为尿道外口、阴茎尿道、吻合口、固定段和不同位置,各有 18、28、48、15 和 9 例尿道成形术。44 例(41.12%)出现尿道狭窄复发。尿道切开术、HMP、EPA、FGU、PFU、TSU 和 PUR 的狭窄复发率分别为 25%、42.11%、42.86%、50%、40%、30.3%和 61.9%。

结论

阴茎成形术后主要的狭窄位置是阴茎和固定段之间的吻合口。阴茎成形术后狭窄的尿道成形术复发率相对较高。

临床试验注册号

EC UZG 2007/434。

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