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Dissecting DNA hypermethylation in cancer.解析癌症中的 DNA 高甲基化。
FEBS Lett. 2011 Jul 7;585(13):2078-86. doi: 10.1016/j.febslet.2010.12.001. Epub 2010 Dec 10.
2
Genomic insights into cancer-associated aberrant CpG island hypermethylation.癌症相关异常 CpG 岛过度甲基化的基因组见解。
Brief Funct Genomics. 2013 May;12(3):174-90. doi: 10.1093/bfgp/els063. Epub 2013 Jan 21.
3
General transcription factor binding at CpG islands in normal cells correlates with resistance to de novo DNA methylation in cancer cells.正常细胞中通用转录因子与 CpG 岛的结合与癌细胞中从头 DNA 甲基化的抗性相关。
Cancer Res. 2010 Feb 15;70(4):1398-407. doi: 10.1158/0008-5472.CAN-09-3406. Epub 2010 Feb 9.
4
Navigating the DNA methylation landscape of cancer.解析癌症 DNA 甲基化图谱。
Trends Genet. 2021 Nov;37(11):1012-1027. doi: 10.1016/j.tig.2021.05.002. Epub 2021 Jun 10.
5
[DNA methylation and cancer].[DNA甲基化与癌症]
Gan To Kagaku Ryoho. 2007 Feb;34(2):145-9.
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Transcriptional overlap links DNA hypomethylation with DNA hypermethylation at adjacent promoters in cancer.转录重叠将 DNA 低甲基化与癌症中相邻启动子的 DNA 高甲基化联系起来。
Sci Rep. 2021 Aug 30;11(1):17346. doi: 10.1038/s41598-021-96844-0.
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The rise and fall of genomic methylation in cancer.癌症中基因组甲基化的起伏
Leukemia. 2004 Feb;18(2):233-7. doi: 10.1038/sj.leu.2403218.
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DNA methylation as a target of epigenetic therapeutics in cancer.DNA 甲基化作为癌症表观遗传治疗的靶点。
Anticancer Agents Med Chem. 2013 Feb;13(2):242-7. doi: 10.2174/1871520611313020009.
9
DNA methylation and cancer.DNA 甲基化与癌症。
Adv Genet. 2010;70:27-56. doi: 10.1016/B978-0-12-380866-0.60002-2.
10
Analysis of promoter CpG island hypermethylation in cancer: location, location, location!分析癌症启动子 CpG 岛甲基化：位置，位置，位置！
Clin Cancer Res. 2011 Jul 1;17(13):4225-31. doi: 10.1158/1078-0432.CCR-10-3394. Epub 2011 May 10.
引用本文的文献
1
Genome-Wide Methylation Patterns in Primary Uveal Melanoma: Development of MethylSig-UM, an Epigenomic Prognostic Signature to Improve Patient Stratification.原发性葡萄膜黑色素瘤的全基因组甲基化模式：甲基化特征UM的开发，一种用于改善患者分层的表观基因组预后特征。
Cancers (Basel). 2024 Jul 25;16(15):2650. doi: 10.3390/cancers16152650.
2
Exportin 4 DNA promoter methylation in liver fibrosis.Exportin 4 基因启动子 DNA 甲基化与肝纤维化。
PLoS One. 2024 May 9;19(5):e0302786. doi: 10.1371/journal.pone.0302786. eCollection 2024.
3
Implications of Cellular Mechanical Memory in Bioengineering.细胞力学记忆在生物工程中的意义。
ACS Biomater Sci Eng. 2023 Nov 13;9(11):5985-5998. doi: 10.1021/acsbiomaterials.3c01007. Epub 2023 Oct 5.
4
Notch, SUMOylation, and ESR-Mediated Signalling Are the Main Molecular Pathways Showing Significantly Different Epimutation Scores between Expressing or Not Oestrogen Receptor Breast Cancer in Three Public EWAS Datasets.Notch、SUMO化和雌激素受体介导的信号传导是在三个公共表观全基因组关联研究数据集的雌激素受体表达或不表达的乳腺癌之间显示出显著不同表观突变评分的主要分子途径。
Cancers (Basel). 2023 Aug 15;15(16):4109. doi: 10.3390/cancers15164109.
5
Systematic pan-cancer analysis identifies as an immunological and prognostic biomarker.系统性泛癌分析将 鉴定为一种免疫和预后生物标志物。 （原文中“identifies”后缺少具体内容）
Ann Transl Med. 2023 Jan 31;11(2):121. doi: 10.21037/atm-22-6318.
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Non-pathogenic microbiota accelerate age-related CpG Island methylation in colonic mucosa.非致病性微生物群加速结直肠黏膜与年龄相关的 CpG 岛甲基化。
Epigenetics. 2023 Dec;18(1):2160568. doi: 10.1080/15592294.2022.2160568. Epub 2022 Dec 26.
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Tracing the Origin of Cell-Free DNA Molecules through Tissue-Specific Epigenetic Signatures.通过组织特异性表观遗传特征追踪游离DNA分子的起源
Diagnostics (Basel). 2022 Jul 29;12(8):1834. doi: 10.3390/diagnostics12081834.
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Mechanisms of myeloid leukemogenesis: Current perspectives and therapeutic objectives.髓系白血病发生机制：当前观点与治疗目标。
Blood Rev. 2023 Jan;57:100996. doi: 10.1016/j.blre.2022.100996. Epub 2022 Aug 2.
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Epigenetic Changes and Functions in Pneumoconiosis.尘肺的表观遗传改变与功能。
Oxid Med Cell Longev. 2022 Jan 20;2022:2523066. doi: 10.1155/2022/2523066. eCollection 2022.
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A pan-cancer analysis revealing the role of TIGIT in tumor microenvironment.一项泛癌症分析揭示了 TIGIT 在肿瘤微环境中的作用。
Sci Rep. 2021 Nov 18;11(1):22502. doi: 10.1038/s41598-021-01933-9.
本文引用的文献
1
DNMT3A mutations in acute myeloid leukemia.DNMT3A 基因突变与急性髓系白血病。
N Engl J Med. 2010 Dec 16;363(25):2424-33. doi: 10.1056/NEJMoa1005143. Epub 2010 Nov 10.
2
Chromosomal, epigenetic and microRNA-mediated inactivation of LRP1B, a modulator of the extracellular environment of thyroid cancer cells.LRP1B 的染色体、表观遗传和 microRNA 介导失活，是甲状腺癌细胞细胞外环境的调节剂。
Oncogene. 2011 Mar 17;30(11):1302-17. doi: 10.1038/onc.2010.512. Epub 2010 Nov 8.
3
Helicobacter pylori infection promotes methylation and silencing of trefoil factor 2, leading to gastric tumor development in mice and humans.幽门螺杆菌感染促进三叶因子 2 的甲基化和沉默，导致小鼠和人类的胃肿瘤发生。
Gastroenterology. 2010 Dec;139(6):2005-17. doi: 10.1053/j.gastro.2010.08.043. Epub 2010 Aug 27.
4
Comprehensive methylome map of lineage commitment from haematopoietic progenitors.造血祖细胞向谱系定向分化的全甲基化组图谱
Nature. 2010 Sep 16;467(7313):338-42. doi: 10.1038/nature09367. Epub 2010 Aug 15.
5
Genome architecture marked by retrotransposons modulates predisposition to DNA methylation in cancer.基因组结构被逆转录转座子标记，调节癌症中 DNA 甲基化的易感性。
Genome Res. 2010 Oct;20(10):1369-82. doi: 10.1101/gr.107318.110. Epub 2010 Aug 17.
6
Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes.DNMT3A 依赖性非启动子 DNA 甲基化促进神经发生基因的转录。
Science. 2010 Jul 23;329(5990):444-8. doi: 10.1126/science.1190485.
7
Conserved role of intragenic DNA methylation in regulating alternative promoters.基因内 DNA 甲基化在调控替代启动子中的保守作用。
Nature. 2010 Jul 8;466(7303):253-7. doi: 10.1038/nature09165.
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Identification of differentially methylated genes in normal prostate tissues from African American and Caucasian men.鉴定非裔美国男性和白种人男性正常前列腺组织中的差异甲基化基因。
Clin Cancer Res. 2010 Jul 15;16(14):3539-47. doi: 10.1158/1078-0432.CCR-09-3342. Epub 2010 Jul 6.
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Contrasting chromatin organization of CpG islands and exons in the human genome.人类基因组中 CpG 岛和外显子的染色质组织对比。
Genome Biol. 2010;11(7):R70. doi: 10.1186/gb-2010-11-7-r70. Epub 2010 Jul 5.
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Down-regulated microRNA-152 induces aberrant DNA methylation in hepatitis B virus-related hepatocellular carcinoma by targeting DNA methyltransferase 1.下调的 microRNA-152 通过靶向 DNA 甲基转移酶 1 诱导乙型肝炎病毒相关肝细胞癌中的异常 DNA 甲基化。
Hepatology. 2010 Jul;52(1):60-70. doi: 10.1002/hep.23660.
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