Hirayama Fumi, Lee Andy H, Oura Asae, Mori Mitsuru, Hiramatsu Naoko, Taniguchi Hiroyuki
Department of Global Health Policy, Graduate School of Medi-cine, University of Tokyo, Bankyo-ku, Tokyo, 113-0033, Japan.
Asia Pac J Clin Nutr. 2010;19(4):572-7.
To investigate the relationship between dietary intake of minerals and the risk of chronic obstructive pulmonary disease (COPD), a case-control study was conducted in central Japan. A total of 278 referred patients (244 men and 34 women) aged 50-75 years with COPD diagnosed within the past four years and 340 community-based controls undertook spirometric measurements of lung function. A structured questionnaire was administered face-to-face to obtain information on demographics and habitual food consumption. Dietary intakes of six major minerals were derived from the Japanese food composition tables. The COPD patients had lower habitual energy-adjusted intakes of calcium, phosphorus and iron than controls, but not sodium. A significant reduction in prevalence of COPD was observed for calcium, with adjusted odds ratio 0.65 (95% confidence interval: 0.37- 0.98) for the highest level versus lowest level of intake. A high iron intake was also inversely associated with the COPD risk. In conclusion, an inverse association was evident between dietary calcium intake and the risk of COPD for Japanese adults.
为了研究矿物质的饮食摄入量与慢性阻塞性肺疾病（COPD）风险之间的关系，在日本中部进行了一项病例对照研究。共有278名年龄在50 - 75岁之间、在过去四年内被诊断为COPD的转诊患者（244名男性和34名女性）以及340名社区对照者接受了肺功能的肺活量测定。通过面对面发放结构化问卷来获取人口统计学信息和习惯性食物消费信息。六种主要矿物质的饮食摄入量来自日本食物成分表。COPD患者经能量调整后的钙、磷和铁习惯性摄入量低于对照组，但钠的摄入量并非如此。观察到钙的COPD患病率显著降低，摄入量最高水平与最低水平相比，调整后的比值比为0.65（95%置信区间：0.37 - 0.98）。高铁摄入量也与COPD风险呈负相关。总之，日本成年人的饮食钙摄入量与COPD风险之间存在明显的负相关。
