Vanderbilt University School of Medicine and the Monroe Carell Jr Children's Hospital at Vanderbilt, Nashville, TN, USA.
J Pediatr Gastroenterol Nutr. 2011 Feb;52(2):162-5. doi: 10.1097/MPG.0b013e3181ec1d2e.
Nongastrointestinal (non-GI) somatic complaints are common in children and adults with functional gastrointestinal disorders (FGIDs). The aim of the present study was to determine whether non-GI somatic complaints in children with functional abdominal pain (FAP) were associated with FGIDs in adolescence and young adulthood.
In a prospective clinic-based study, children and adolescents (ages 8-16 years) with FAP (n = 188) and well controls (n = 61) completed a validated measure of somatic symptoms. Participants were assessed 4 to 15 years later (as older adolescents and young adults) for presence of current FGIDs as defined by the Rome III criteria.
Of the 188 youths with pediatric FAP, 35.6% met criteria for FGIDs at follow-up. Initial levels of non-GI somatic symptoms were significantly higher in pediatric FAP participants who subsequently met criteria for FGIDs at follow-up compared with controls and pediatric FAP participants who did not meet criteria for FGIDs at follow-up.
The association of non-GI somatic symptoms with FAP in children may identify a group that is at risk for FGIDs later in life.
非胃肠道（非 GI）躯体症状在功能性胃肠疾病（FGIDs）的儿童和成人中很常见。本研究旨在确定功能性腹痛（FAP）儿童的非 GI 躯体症状是否与青少年和年轻成人时期的 FGIDs 有关。
在一项前瞻性基于诊所的研究中，患有 FAP（n=188）和健康对照组（n=61）的儿童和青少年（8-16 岁）完成了一项躯体症状的验证性测量。参与者在 4 至 15 年后（作为青少年和年轻成人）根据罗马 III 标准评估当前 FGIDs 的存在情况。
在随访的 188 名患有儿科 FAP 的青少年中，35.6%符合 FGIDs 的标准。与对照组和未符合 FGIDs 标准的儿科 FAP 参与者相比，随后符合 FGIDs 标准的儿科 FAP 参与者的初始非 GI 躯体症状水平显著更高。
儿童非 GI 躯体症状与 FAP 的关联可能会识别出一组在以后的生活中存在 FGIDs 风险的人群。
