Sağlam Murat, Öncel Selim, Gündoğdu Zuhal
Pediatrics and Child Health, Kocaeli University, Izmit, TUR.
Cureus. 2022 Apr 2;14(4):e23765. doi: 10.7759/cureus.23765. eCollection 2022 Apr.
Introduction In order to better understand the barriers to influenza vaccination, we have designed a study to investigate pregnant women's knowledge, attitude, perceptions, and concerns towards the inactivated influenza vaccine. Materials and methods In this prospective study, carried out between July 1, 2019, and December 31, 2019, 252 pregnant women (≥12 weeks of gestational age), who had consented to be enrolled in the study, were asked to complete an interviewer-administered questionnaire during their stay in the hospital ward. Results The lack of information about influenza vaccines (59.4%) was in the first rank among the reasons for personal and parental vaccine rejection. Most (65.1%) pregnant women either did not believe in or had doubts about the efficiency of the influenza vaccine during gestation. Most of them (80.9%) either were not sure about or did not have much confidence in the prenatally inoculated vaccine's ability to protect their babies postnatally. Some (25.6%) participants attributed their vaccinal unwillingness to fear of adverse effects, and some (11.5%) deemed gestational influenza immunization unnecessary because of their tendency to underestimate the grave consequences of influenza contracted by infants within the first six months of life. The higher the education level, the higher was the knowledge of and the willingness to be immunized against influenza. Discussion It is known that about one-third of pregnant women in Turkey have never heard of the influenza vaccine. Unawareness of influenza vaccination in pregnancy is significantly related to vaccine uptake in Japan. Patient education on knowledge of influenza and influenza vaccination has a booster effect on vaccination rates. Had the influenza vaccine been routinely administered to pregnant women in Turkey, the lives of the majority of the women who died of influenza in the influenza A (H1N1) pandemic in 2009 would have been saved. Low-risk perception is quoted as one of the main reasons for influenza vaccine refusal during pregnancy, which was also the case in our study. Concordant with the current literature, the education level and household income were correlated with the level of influenza vaccination uptake. Pregnant women's fear of adverse effects of the influenza vaccine might extend to the fear of birth defects. Conclusion The acceptance of influenza vaccines by pregnant women is a consequence of complex interactions of various factors. Giving necessary information to pregnant women is one of the most important factors that can increase influenza vaccine uptake. For this reason, it should be ensured that the efficacy and safety data of the influenza vaccine are more widely included in vocational training activities of health personnel and in prenatal care textbooks and guidelines.
引言 为了更好地了解流感疫苗接种的障碍,我们设计了一项研究,以调查孕妇对灭活流感疫苗的知识、态度、认知和担忧。
材料与方法 在这项前瞻性研究中,于2019年7月1日至2019年12月31日期间,252名同意参与研究的孕妇(孕周≥12周)在住院病房期间被要求完成一份由访谈员填写的问卷。
结果 在个人及家长拒绝接种疫苗的原因中,缺乏流感疫苗信息(59.4%)位居首位。大多数(65.1%)孕妇要么不相信流感疫苗在孕期的有效性,要么对此表示怀疑。她们中的大多数(80.9%)要么不确定产前接种的疫苗能否在产后保护其婴儿,要么对此信心不足。一些参与者(25.6%)将其不愿接种疫苗归因于对不良反应的恐惧,一些(11.5%)认为孕期流感免疫不必要,因为她们倾向于低估婴儿在出生后前六个月感染流感的严重后果。教育水平越高,对流感的知识了解程度和接种意愿就越高。
讨论 众所周知,土耳其约三分之一的孕妇从未听说过流感疫苗。孕期对流感疫苗的不了解与日本的疫苗接种率显著相关。对患者进行流感及流感疫苗知识教育对疫苗接种率有促进作用。如果在土耳其对孕妇常规接种流感疫苗,那么在2009年甲型H1N1流感大流行中死于流感的大多数女性的生命本可挽救。低风险认知被认为是孕期拒绝接种流感疫苗的主要原因之一,本研究中也是如此。与当前文献一致,教育水平和家庭收入与流感疫苗接种率相关。孕妇对流感疫苗不良反应的恐惧可能延伸至对出生缺陷的恐惧。
结论 孕妇对流感疫苗的接受是多种因素复杂相互作用的结果。向孕妇提供必要信息是提高流感疫苗接种率的最重要因素之一。因此,应确保流感疫苗的有效性和安全性数据更广泛地纳入卫生人员的职业培训活动以及产前护理教科书和指南中。