[Vaccination under immunosuppressive therapy of chronic inflammatory diseases].

Immune-mediated inflammatory diseases and applied immunosuppressive or modulating medications predispose patients for more frequent and more severe infections. Partly, these can be prevented by vaccinations. However immunization rates in daily life are low. The indication for vaccination, the capacity of sufficient antibody response and possible adverse reactions--such as vaccination-induced infection in live-vaccines--must be carefully evaluated and timing should be planned accordingly. In addition to vaccinations according general recommendation patients with immunosuppression benefit from vaccinations against seasonal influenza and S. pneumoniae. Induction of flares of the underlying disease after vaccination could not be confirmed.