合成电路、器件和模块。
Synthetic circuits, devices and modules.
机构信息
National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
出版信息
Protein Cell. 2010 Nov;1(11):974-8. doi: 10.1007/s13238-010-0133-8. Epub 2010 Dec 10.
Abstract
The aim of synthetic biology is to design artificial biological systems for novel applications. From an engineering perspective, construction of biological systems of defined functionality in a hierarchical way is fundamental to this emerging field. Here, we highlight some current advances on design of several basic building blocks in synthetic biology including the artificial gene control elements, synthetic circuits and their assemblies into devices and modules. Such engineered basic building blocks largely expand the synthetic toolbox and contribute to our understanding of the underlying design principles of living cells.
摘要
合成生物学的目标是设计用于新型应用的人工生物系统。从工程学的角度来看，以分层的方式构建具有明确定义功能的生物系统是这一新兴领域的基础。在这里，我们重点介绍了在合成生物学中设计几个基本构建块方面的一些最新进展，包括人工基因调控元件、合成电路及其组装成器件和模块。这些经过工程设计的基本构建块在很大程度上扩展了合成工具箱，并有助于我们理解活细胞的基本设计原则。
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