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青少年戒烟行为支持与简短建议的整群随机试验的试验方案和初步结果

Trial protocol and preliminary results for a cluster randomised trial of behavioural support versus brief advice for smoking cessation in adolescents.

作者信息

Markham Wolfgang A, Bridle Christopher, Grimshaw Gillian, Stanton Alan, Aveyard Paul

机构信息

School of Health and Social Studies, University of Warwick, Coventry, CV4 7AL, UK.

出版信息

BMC Res Notes. 2010 Dec 14;3:336. doi: 10.1186/1756-0500-3-336.

DOI:10.1186/1756-0500-3-336
PMID:21156068
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3022813/
Abstract

BACKGROUND

Many young people report they want to stop smoking and have tried to do so, but most of their quit attempts fail. For adult smokers, there is strong evidence that group behavioural support enhances quit rates. However, it is uncertain whether group behavioural support enhances abstinence in young smokers trying to quit.

FINDINGS

A cluster randomised trial for young people trying to stop smoking to compare the efficacy of a school-based 9 week intensive group behavioural support course versus a school-based 7 week brief advice only course. Participants were assessed for evidence of tobacco addiction and nicotine replacement therapy (NRT) was used if it was deemed appropriate by the therapist. Both types of course aimed to recruit approximately one hundred participants from approximately ten schools.The primary outcome was successful quitting at 4 weeks after quit day judged according to the Russell standard. Had the trial been completed, abstinence at 6 months after quit day and the relationships between successful quit attempts and 1) psychological assessments of dependence prior to quitting 2) salivary cotinine concentration prior to quitting and 3) sociodemographic characteristics would also have been assessed. The proportion of participants who stopped smoking in each arm of the trial were compared using Chi square tests.The trial was stopped shortly after it had started because funding to support the therapists running the stop smoking group behavioural support programme was withdrawn. Only three stop smoking courses were completed (two group support courses and one brief advice pharmacotherapy course). Seventeen participants in total entered the trial. At the end of the courses, one participant (10%) attending the group support programme had stopped smoking and no participant attending the brief advice programme had stopped smoking.

DISCUSSION

The trial was stopped so we were unable to determine whether group support helped more young people to stop smoking than brief advice. Engagement and recruitment of participants proved much more difficult than had been anticipated. Fifteen of the seventeen participants reported that quitting smoking was either pretty important or very important to them. Thus, the stop smoking success rate could, nevertheless, be considered disappointing.

TRIAL REGISTRATION

Current Controlled Trials ISRCTN25181936.

摘要

背景

许多年轻人表示他们想戒烟并已尝试过,但大多数戒烟尝试都失败了。对于成年吸烟者,有充分证据表明团体行为支持可提高戒烟率。然而,团体行为支持是否能提高试图戒烟的年轻吸烟者的戒断率尚不确定。

研究结果

一项针对试图戒烟的年轻人的整群随机试验,比较以学校为基础的为期9周的强化团体行为支持课程与以学校为基础的为期7周的仅提供简短建议课程的效果。对参与者进行烟草成瘾证据评估,治疗师认为合适时使用尼古丁替代疗法(NRT)。两种课程都旨在从大约十所学校招募约一百名参与者。主要结局是根据拉塞尔标准判断在戒烟日4周后成功戒烟。如果试验完成,还将评估戒烟日6个月后的戒断情况以及成功戒烟尝试与以下因素之间的关系:1)戒烟前对依赖的心理评估;2)戒烟前唾液可替宁浓度;3)社会人口学特征。使用卡方检验比较试验各臂中戒烟的参与者比例。试验开始后不久就停止了,因为支持开展戒烟团体行为支持项目的治疗师的资金被撤回。总共只完成了三门戒烟课程(两门团体支持课程和一门简短建议药物治疗课程)。共有17名参与者进入试验。课程结束时,参加团体支持项目的一名参与者(10%)成功戒烟,参加简短建议项目的参与者无人戒烟。

讨论

试验停止了,所以我们无法确定团体支持是否比简短建议更有助于更多年轻人戒烟。事实证明,参与者的参与和招募比预期困难得多。17名参与者中有15人表示戒烟对他们来说要么相当重要要么非常重要。因此,戒烟成功率仍可能被认为令人失望。

试验注册

当前对照试验ISRCTN25181936。

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2
Low-income groups and behaviour change interventions: a review of intervention content, effectiveness and theoretical frameworks.低收入群体和行为改变干预措施:干预内容、效果和理论框架的综述。
J Epidemiol Community Health. 2009 Aug;63(8):610-22. doi: 10.1136/jech.2008.078725. Epub 2009 Apr 21.
3
A Scotland-wide pilot programme of smoking cessation services for young people: process and outcome evaluation.一项面向苏格兰年轻人的戒烟服务全国试点项目:过程与结果评估。
Addiction. 2008 Nov;103(11):1866-74. doi: 10.1111/j.1360-0443.2008.02316.x. Epub 2008 Aug 14.
4
The challenges of getting youth cessation services right.
Addiction. 2007 Jul;102(7):1023-4. doi: 10.1111/j.1360-0443.2007.01921.x.
5
Tobacco cessation interventions for young people.针对年轻人的戒烟干预措施。
Cochrane Database Syst Rev. 2006 Oct 18(4):CD003289. doi: 10.1002/14651858.CD003289.pub4.
6
Use of nicotine replacement therapy in socioeconomically deprived young smokers: a community-based pilot randomised controlled trial.社会经济条件较差的年轻吸烟者使用尼古丁替代疗法:一项基于社区的试点随机对照试验。
Tob Control. 2006 Oct;15(5):373-6. doi: 10.1136/tc.2005.014514.
7
Designing smoking cessation services for school-age smokers: A survey and qualitative study.为学龄吸烟者设计戒烟服务:一项调查与定性研究。
Nicotine Tob Res. 2006 Aug;8(4):539-46. doi: 10.1080/14622200600789817.
8
Ambivalence and uncertainty: experiences of and attitudes towards addiction and smoking cessation in the mid-to-late teens.
Health Educ Res. 2006 Apr;21(2):181-91. doi: 10.1093/her/cyh054. Epub 2005 Aug 17.
9
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Pediatrics. 2005 Apr;115(4):981-9. doi: 10.1542/peds.2004-0981.
10
Outcome criteria in smoking cessation trials: proposal for a common standard.戒烟试验的结果标准:通用标准提案。
Addiction. 2005 Mar;100(3):299-303. doi: 10.1111/j.1360-0443.2004.00995.x.