由霍乱弧菌 O137 引起的坏死性筋膜炎的罕见病例。
Unusual case of necrotizing fasciitis caused by Vibrio cholerae O137.
机构信息
Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche, Centro di Referenza Nazionale Controllo Microbiologico e Chimico Molluschi Bivalvi Vivi (CEREM), via Cupa di Posatora 3, 60126 Ancona, Italy.
出版信息
J Clin Microbiol. 2011 Feb;49(2):757-9. doi: 10.1128/JCM.02257-10. Epub 2010 Dec 15.
Abstract
We report a case of necrotizing fasciitis caused by Vibrio cholerae O137 in an immunocompromised 49-year-old man. The infection was acquired following a minor traumatic injury and exposure to seawater during the summer of 2009 in Italy. Although highly immunocompromised, the patient survived. The strain was cytotoxic, invasive, and adhesive and contained a fragment of the El Tor-like hemolysin (El Tor hlyA) gene.
摘要
我们报告了一例由创伤后感染创伤弧菌引起的坏死性筋膜炎，患者为 49 岁免疫功能低下男性。该感染发生于 2009 年夏季在意大利，患者在接触海水的情况下发生了轻微创伤。尽管患者免疫功能严重低下，但仍存活下来。该菌株具有细胞毒性、侵袭性和黏附性，并含有一段类似于 El Tor 样溶血素（El Tor hlyA）的基因片段。
相似文献
1
Unusual case of necrotizing fasciitis caused by Vibrio cholerae O137.由霍乱弧菌 O137 引起的坏死性筋膜炎的罕见病例。
J Clin Microbiol. 2011 Feb;49(2):757-9. doi: 10.1128/JCM.02257-10. Epub 2010 Dec 15.
2
A rare case of necrotizing fasciitis caused by Vibrio cholerae O8 in an immunocompetent patient.一例免疫功能正常患者由霍乱弧菌O8引起的坏死性筋膜炎罕见病例。
Wien Klin Wochenschr. 2016 Oct;128(19-20):728-730. doi: 10.1007/s00508-016-1060-3. Epub 2016 Sep 7.
3
Bacteremic necrotizing fasciitis caused by Vibrio cholerae serogroup O56 in a patient with liver cirrhosis.一名肝硬化患者由霍乱弧菌O56血清群引起的菌血症性坏死性筋膜炎。
J Formos Med Assoc. 2004 Dec;103(12):935-8.
4
Necrotizing fasciitis due to Vibrio cholerae non-O1/non-O139 after exposure to Austrian bathing sites.暴露于奥地利浴场后由非O1/非O139群霍乱弧菌引起的坏死性筋膜炎。
Wien Klin Wochenschr. 2016 Feb;128(3-4):141-5. doi: 10.1007/s00508-015-0944-y. Epub 2016 Jan 29.
5
Necrotizing fasciitis and septic shock caused by Vibrio cholerae acquired in San Diego, California.在加利福尼亚州圣地亚哥感染霍乱弧菌引起的坏死性筋膜炎和感染性休克。
West J Med. 1995 Oct;163(4):375-7.
6
Hemolysin and the multifunctional autoprocessing RTX toxin are virulence factors during intestinal infection of mice with Vibrio cholerae El Tor O1 strains.溶血素和多功能自加工RTX毒素是霍乱弧菌El Tor O1菌株感染小鼠肠道期间的毒力因子。
Infect Immun. 2007 Oct;75(10):5035-42. doi: 10.1128/IAI.00506-07. Epub 2007 Aug 13.
7
El Tor Biotype Activates the Caspase-11-Independent Canonical Nlrp3 and Pyrin Inflammasomes.埃尔托生物型激活半胱天冬酶-11 非依赖性经典 Nlrp3 和 Pyrin 炎性小体。
Front Immunol. 2019 Oct 29;10:2463. doi: 10.3389/fimmu.2019.02463. eCollection 2019.
8
Molecular characterization of serogrouping and virulence genes of Malaysian Vibrio cholerae isolated from different sources.从不同来源分离的马来西亚霍乱弧菌血清群和毒力基因的分子特征
J Gen Appl Microbiol. 2009 Dec;55(6):419-25. doi: 10.2323/jgam.55.419.
9
Analysis of Vibrio cholerae genome sequences reveals unique rtxA variants in environmental strains and an rtxA-null mutation in recent altered El Tor isolates.霍乱弧菌基因组序列分析揭示了环境菌株中独特的 rtxA 变体，以及近期变异埃尔托弧菌分离株中存在 rtxA 缺失突变。
mBio. 2013 Apr 16;4(2):e00624. doi: 10.1128/mBio.00624-12.
10
Distribution of genes encoding cholera toxin, zonula occludens toxin, accessory cholera toxin, and El Tor hemolysin in Vibrio cholerae of diverse origins.不同来源霍乱弧菌中编码霍乱毒素、小带闭合毒素、辅助霍乱毒素和埃尔托溶血素的基因分布。
Microb Pathog. 1995 Mar;18(3):231-5. doi: 10.1016/s0882-4010(95)90076-4.
引用本文的文献
1
Non-toxigenic - just another cause of vibriosis or a potential new pandemic?非产毒型——弧菌病的另一个病因还是潜在的新大流行病因？
Arch Clin Cases. 2025 Feb 6;12(1):5-16. doi: 10.22551/2025.46.1201.10305. eCollection 2025.
2
Vibrio cholerae-Associated Necrotizing Fasciitis in an Immunocompromised Individual: Trivial Exposure Leading to a Life-Threatening Illness.免疫功能低下个体中的霍乱弧菌相关性坏死性筋膜炎：轻微暴露引发危及生命的疾病
Cureus. 2024 Sep 19;16(9):e69727. doi: 10.7759/cureus.69727. eCollection 2024 Sep.
3
Bacteremia: An Enigma in Cholera-Endemic African Countries.菌血症：霍乱流行的非洲国家中的一个谜团。
Trop Med Infect Dis. 2024 May 2;9(5):103. doi: 10.3390/tropicalmed9050103.
4
Non-serogroup O1/O139 agglutinable Vibrio cholerae: a phylogenetically and genealogically neglected yet emerging potential pathogen of clinical relevance.非 O1/O139 群可凝集霍乱弧菌：一种在系统发生和系统发育上被忽视但具有临床相关性的新兴潜在病原体。
Arch Microbiol. 2022 May 14;204(6):323. doi: 10.1007/s00203-022-02866-1.
5
Intensive care management of a patient with necrotizing fasciitis due to non-O1/O139 Vibrio cholerae after traveling to Taiwan: a case report.一名前往台湾后感染非O1/O139型霍乱弧菌所致坏死性筋膜炎患者的重症监护管理：病例报告
BMC Infect Dis. 2020 Aug 24;20(1):618. doi: 10.1186/s12879-020-05343-6.
6
Phenotypic and Genotypic Antimicrobial Resistance Traits of Non-O1/Non-O139 Isolated From a Large Austrian Lake Frequently Associated With Cases of Human Infection.从奥地利一个经常与人类感染病例相关的大型湖泊中分离出的非O1/非O139型的表型和基因型抗菌耐药特征
Front Microbiol. 2019 Nov 8;10:2600. doi: 10.3389/fmicb.2019.02600. eCollection 2019.
7
Antimicrobial Susceptibility among Urban Wastewater and Wild Shellfish Isolates of Non-O1/Non-O139 from La Rance Estuary (Brittany, France).法国布列塔尼地区朗斯河口城市污水和野生贝类中分离出的非O1/非O139霍乱弧菌的抗菌药敏性
Front Microbiol. 2017 Sep 12;8:1637. doi: 10.3389/fmicb.2017.01637. eCollection 2017.
8
A rare case of necrotizing fasciitis caused by Vibrio cholerae O8 in an immunocompetent patient.一例免疫功能正常患者由霍乱弧菌O8引起的坏死性筋膜炎罕见病例。
Wien Klin Wochenschr. 2016 Oct;128(19-20):728-730. doi: 10.1007/s00508-016-1060-3. Epub 2016 Sep 7.
9
Extraintestinal Infections Caused by Non-toxigenic Vibrio cholerae non-O1/non-O139.非产毒霍乱弧菌非O1/非O139引起的肠外感染
Front Microbiol. 2016 Feb 11;7:144. doi: 10.3389/fmicb.2016.00144. eCollection 2016.
10
Necrotizing fasciitis due to Vibrio cholerae non-O1/non-O139 after exposure to Austrian bathing sites.暴露于奥地利浴场后由非O1/非O139群霍乱弧菌引起的坏死性筋膜炎。
Wien Klin Wochenschr. 2016 Feb;128(3-4):141-5. doi: 10.1007/s00508-015-0944-y. Epub 2016 Jan 29.
本文引用的文献
1
Prevalence and virulence properties of non-O1 non-O139 Vibrio cholerae strains from seafood and clinical samples collected in Italy.从意大利收集的海鲜和临床样本中分离出的非O1非O139霍乱弧菌菌株的流行情况及毒力特性
Int J Food Microbiol. 2009 Jun 1;132(1):47-53. doi: 10.1016/j.ijfoodmicro.2009.03.014. Epub 2009 Mar 31.
2
Marine bacteria as a leading cause of necrotizing fasciitis in coastal areas of South Korea.海洋细菌是韩国沿海地区坏死性筋膜炎的主要病因。
Am J Trop Med Hyg. 2009 Apr;80(4):646-50.
3
Necrotizing fasciitis in patients with liver cirrhosis: predominance of monomicrobial Gram-negative bacillary infections.肝硬化患者的坏死性筋膜炎：以单一微生物革兰氏阴性杆菌感染为主。
Diagn Microbiol Infect Dis. 2008 Oct;62(2):219-25. doi: 10.1016/j.diagmicrobio.2008.05.016. Epub 2008 Jul 23.
4
Interactions of clinical and environmental Aeromonas isolates with Caco-2 and HT29 intestinal epithelial cells.临床分离株和环境分离株气单胞菌与Caco-2和HT29肠上皮细胞的相互作用。
Lett Appl Microbiol. 2007 Oct;45(4):405-10. doi: 10.1111/j.1472-765X.2007.02199.x.
5
New consensus guidelines from the Clinical and Laboratory Standards Institute for antimicrobial susceptibility testing of infrequently isolated or fastidious bacteria.临床和实验室标准协会发布的关于罕见分离或苛求菌抗菌药敏试验的新共识指南。
Clin Infect Dis. 2007 Jan 15;44(2):280-6. doi: 10.1086/510431. Epub 2006 Dec 7.
6
O1 and non-O1 Vibrio cholerae bacteremia produced by hemolytic strains.由溶血型菌株引起的O1群和非O1群霍乱弧菌菌血症。
Diagn Microbiol Infect Dis. 2006 Feb;54(2):145-8. doi: 10.1016/j.diagmicrobio.2005.08.008. Epub 2006 Jan 19.
7
[Severe sepsis and cellulitis caused by Vibrio cholerae no-01 in an immunocompetent patient].
Med Clin (Barc). 2005 Nov 19;125(18):717. doi: 10.1016/s0025-7753(05)72164-3.
8
A biochemical protocol for the isolation and identification of current species of Vibrio in seafood.一种用于分离和鉴定海鲜中当前弧菌种类的生化实验方案。
J Appl Microbiol. 2003;95(6):1277-84. doi: 10.1046/j.1365-2672.2003.02105.x.
9
Independent prognostic factors for fatality in patients with invasive vibrio cholerae non-O1 infections.侵袭性非O1群霍乱弧菌感染患者死亡的独立预后因素。
J Microbiol Immunol Infect. 2003 Jun;36(2):117-22.
10
Vibrio cholerae O2 sepsis in a patient with AIDS.
Eur J Clin Microbiol Infect Dis. 1999 Mar;18(3):203-5. doi: 10.1007/s100960050259.
Zotero 插件