Heidecke Sabine, Stippel Dirk L, Hoelscher Arnulf H, Wedemeyer Inga, Dienes Hans-Peter, Drebber Uta
Sabine Heidecke, Dirk L Stippel, Arnulf H Hoelscher, Department of General-, Visceral- and Cancer Surgery, University Hospital of Cologne, Cologne 50937, Germany.
World J Hepatol. 2010 Jun 27;2(6):246-50. doi: 10.4254/wjh.v2.i6.246.
To investigate the simultaneous occurrence of hepatocellular carcinoma and non-Hodgkin's lymphoma, we report the case of a 70 year old patient with a primary diagnosis of non-Hodgkin's lymphoma in 2002. In a routine follow up investigation of his chronic lymphocytic leukemia a newly detected mass in the Couinaud's segments 2 and 3 was found. No hepatitis C virus or hepatitis B virus infection or cirrhosis was evident. After laparoscopic segmentectomy the histological examination revealed a hepatocellular carcinoma. While the relation between liver parenchyma damages and hepatocellular carcinoma or non-Hodgkin's lymphoma is well known, only a few publications have focused on the coexistence of hepatocellular carcinoma and non-Hodgkin's lymphoma. With this case we demonstrate the coexistence of these diseases without having a predamaged liver parenchyma.
为了研究肝细胞癌与非霍奇金淋巴瘤的同时发生情况,我们报告了一例2002年初步诊断为非霍奇金淋巴瘤的70岁患者的病例。在对其慢性淋巴细胞白血病进行常规随访检查时,发现肝Couinaud 2段和3段有一个新发现的肿块。未发现丙型肝炎病毒或乙型肝炎病毒感染或肝硬化迹象。经腹腔镜肝段切除术后,组织学检查显示为肝细胞癌。虽然肝实质损伤与肝细胞癌或非霍奇金淋巴瘤之间的关系已为人熟知,但仅有少数文献关注肝细胞癌与非霍奇金淋巴瘤的共存情况。通过本病例,我们证明了在没有肝实质预先损伤的情况下这两种疾病的共存。