Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, Canada.
Pediatr Radiol. 2011 Jun;41(6):759-68. doi: 10.1007/s00247-010-1925-y. Epub 2010 Dec 16.
Positron emission tomography (PET) using [F-18]2-fluoro-2-deoxyglucose (FDG) fused with CT ((18)F-FDG PET/CT) has been widely adopted in oncological imaging. However, it is known that benign lesions and other metabolically active tissues, such as brown adipose tissue (BAT), can accumulate (18)F-FDG, potentially resulting in false-positive interpretation. Previous studies have reported that (18)F-FDG uptake in BAT is more common in children than in adults. We illustrate BAT FDG uptake in various anatomical locations in children and adolescents. We also review what is known about the effects of patient-related physical attributes and environmental temperatures on BAT FDG uptake, and discuss methods used to reduce BAT FDG uptake on (18)F-FDG PET.
正电子发射断层扫描（PET）使用[F-18]2-氟-2-脱氧葡萄糖（FDG）与 CT 融合（18F-FDG PET/CT）已广泛应用于肿瘤学成像。然而，众所周知，良性病变和其他代谢活跃的组织，如棕色脂肪组织（BAT），也可以积累 18F-FDG，可能导致假阳性解读。先前的研究报告称，儿童比成人更常见 BAT 摄取 18F-FDG。我们展示了儿童和青少年不同解剖部位的 BAT FDG 摄取情况。我们还回顾了与患者相关的身体特征和环境温度对 BAT FDG 摄取的影响，讨论了用于减少 18F-FDG PET 上 BAT FDG 摄取的方法。
