Center for Diagnostic and Therapeutic Endoscopy, Department of Surgery, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, Tokyo, 160-8582, Japan.
J Hepatobiliary Pancreat Sci. 2011 May;18(3):339-45. doi: 10.1007/s00534-010-0362-5.
BACKGROUND/PURPOSE: While endoscopic sphincterotomy (EST) is performed worldwide for the removal of common bile duct stones, many biliary endoscopists hesitate to regard endoscopic papillary balloon dilation (EPBD) as a standard procedure for treatment. Therefore, the aim of this review is to re-evaluate the status of EPBD for the treatment of common bile duct stones.
A major benefit of EPBD is preservation of papillary function, which is not complete but may be greater than that after EST. The disadvantages of EPBD compared with EST are that EPBD is difficult to use for the removal of larger stones because of the smaller biliary opening, it requires more frequent use of mechanical lithotripsy, and it is associated with a higher incidence of pancreatitis, although the risks of bleeding and perforation are low. Since the biliary sphincter is easily dilated with a balloon catheter, EPBD may be effective for patients with anatomic anomalies, such as after gastric bypass surgery or in the presence of a periampullary diverticulum. No standard procedure exists to reduce the risk of acute pancreatitis with EPBD.
EPBD is feasible, however, we must pursue less hazardous techniques of papillary balloon dilation. Furthermore, we must understand the benefits and limitations of EPBD and determine whether it could provide clinical benefits for long-term complications.
背景/目的:虽然内镜下括约肌切开术(EST)在全球范围内用于清除胆总管结石,但许多胆道内镜医生仍对内镜乳头气囊扩张术(EPBD)作为治疗的标准程序持犹豫态度。因此,本综述的目的是重新评估 EPBD 治疗胆总管结石的现状。
EPBD 的一个主要优点是保留了乳头功能,尽管不完全,但可能比 EST 后更大。与 EST 相比,EPBD 的缺点是由于胆管开口较小,EPBD 难以用于清除较大的结石,需要更频繁地使用机械碎石术,并且胰腺炎的发生率较高,尽管出血和穿孔的风险较低。由于球囊导管很容易扩张胆管括约肌,EPBD 可能对解剖异常的患者有效,例如胃旁路手术后或存在壶腹周围憩室时。目前尚无标准程序可降低 EPBD 相关急性胰腺炎的风险。
EPBD 是可行的,然而,我们必须寻求更安全的乳头气囊扩张技术。此外,我们必须了解 EPBD 的益处和局限性,并确定其是否能为长期并发症提供临床获益。