Lai Kwok-Hung, Chan Hoi-Hung, Tsai Tzung-Jiun, Cheng Jin-Shiung, Hsu Ping-I
Kwok-Hung Lai, Hoi-Hung Chan, Tzung-Jiun Tsai, Jin-Shiung Cheng, Ping-I Hsu, Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan.
World J Gastrointest Endosc. 2015 Feb 16;7(2):77-86. doi: 10.4253/wjge.v7.i2.77.
Although endoscopic sphincterotomy (EST) is still considered as a gold standard treatment for common bile duct (CBD) stones in western guideline, endoscopic papillary balloon dilation (EPBD) is commonly used by the endoscopists in Asia as the first-line treatment for CBD stones. Besides the advantages of a technical easy procedure, endoscopic papillary large balloon dilation (EPLBD) can facilitate the removal of large CBD stones. The indication of EPBD is now extended from removal of the small stones by using traditional balloon, to removal of large stones and avoidance of lithotripsy by using large balloon alone or after EST. According to the reports of antegrade papillary balloon dilatation, balloon dilation itself is not the cause of pancreatitis. On the contrary, adequate dilation of papillary orifice can reduce the trauma to the papilla and pancreas by the basket or lithotripter during the procedure of stone extraction. EPLBD alone is as effective as EPLBD with limited EST. Longer ballooning time may be beneficial in EPLBD alone to achieve adequate loosening of papillary orifice. The longer ballooning time does not increase the risk of pancreatitis but may reduce the bleeding episodes in patients with coagulopathy. Slowly inflation of the balloon, but not exceed the diameter of bile duct and tolerance of the patients are important to prevent the complication of perforation. EPBLD alone or with EST are not the sphincter preserved procedures, regular follow up is necessary for early detection and management of CBD stones recurrence.
尽管在西方指南中,内镜括约肌切开术(EST)仍被视为胆总管(CBD)结石的金标准治疗方法,但在亚洲,内镜乳头球囊扩张术(EPBD)被内镜医师普遍用作CBD结石的一线治疗方法。除了操作技术简单的优点外,内镜乳头大球囊扩张术(EPLBD)还可以促进大的CBD结石的取出。EPBD的适应证现已从使用传统球囊取出小结石,扩展到单独使用大球囊或在EST后取出大结石并避免碎石术。根据顺行乳头球囊扩张术的报道,球囊扩张本身不是胰腺炎的病因。相反在取石过程中,乳头开口的充分扩张可以减少网篮或碎石器对乳头和胰腺的创伤。单独的EPLBD与有限的EST联合EPLBD一样有效。在单独的EPLBD中,较长的球囊扩张时间可能有助于使乳头开口充分松弛。较长的球囊扩张时间不会增加胰腺炎的风险,但可能会减少凝血功能障碍患者的出血事件。缓慢充盈球囊,但不超过胆管直径和患者的耐受程度,对于预防穿孔并发症很重要。单独的EPBLD或与EST联合使用都不是保留括约肌的手术,需要定期随访以早期发现和处理CBD结石复发。