肾移植患者行体外受精-单胚胎移植后活产：病例报告及文献复习。
Live birth after in vitro fertilization and single embryo transfer in a kidney transplant patient: a case report and review of the literature.
机构信息
Department of Clinical Gynaecologic Endocrinology and Reproductive Medicine, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
出版信息
J Assist Reprod Genet. 2011 Apr;28(4):351-3. doi: 10.1007/s10815-010-9521-5. Epub 2010 Dec 16.
Abstract
BACKGROUND
To present a successful case of in vitro fertilization (IVF) and single embryo transfer (SET) in a kidney transplant (NTX) patient and review of the literature.
METHODS
Case report and review of the literature.
SETTING
IVF-Unit in a university medical center.
PATIENT(S): A 31 year-old nulliparous woman with primary infertility and a history of two kidney transplants.
INTERVENTION(S): IVF-SET MAIN OUTCOME MEASURE(S): Live birth, renal transplant function.
RESULTS(S): IVF-SET resulted in a pregnancy with labor induction and cesarean delivery in the 37th week of gestation due to rising serum creatinine. There was no significant maternal or fetal morbidity.
CONCLUSION(S): Successful IVF-SET is possible in NTX patients. To date, including this case, five cases of IVF in NTX patients have been reported in the literature without an apparently increased renal morbidity.
摘要
背景
介绍一例肾移植（NTX）患者接受体外受精（IVF）和单胚胎移植（SET）成功的病例，并复习文献。
方法
病例报告和文献复习。
地点
大学医学中心的 IVF 单位。
患者
一名 31 岁、原发性不孕、有两次肾移植史的未产妇。
干预措施
IVF-SET。
主要观察指标
活产，肾移植功能。
结果
IVF-SET 导致妊娠，因血清肌酐升高，于 37 孕周行引产和剖宫产术。母婴均无明显发病率。
结论
NTX 患者可行 IVF-SET。迄今为止，包括本例在内，文献中已有 5 例 NTX 患者接受 IVF 治疗的报道，肾功能异常发病率似乎并未增加。
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