Supplement Safety Solutions, 47 Wildwood Drive, Bedford, MA 01730, USA.
J Int Soc Sports Nutr. 2010 Dec 16;7:40. doi: 10.1186/1550-2783-7-40.
The purpose of this study was to compare the effects of supplementation with Gaspari Nutrition's SOmaxP Maximum Performance™ (SOmaxP) versus a comparator product (CP) containing an equal amount of creatine (4 g), carbohydrate (39 g maltodextrin), and protein (7 g whey protein hydrolysate) on muscular strength, muscular endurance, and body composition during nine weeks of intense resistance training.
Using a prospective, randomized, double-blind design, 20 healthy men (mean ± SD age, height, weight, % body fat: 22.9 ± 2.6 y, 178.4 ± 5.7 cm, 80.5 ± 6.6 kg, 16.6 ± 4.0%) were matched for age, body weight, resistance training history, bench press strength, bench press endurance, and percent body fat and then randomly assigned via the ABBA procedure to ingest 1/2 scoop (dissolved in 15 oz water) of SOmaxP or CP prior to, and another 1/2 scoop (dissolved in 15 oz water) during resistance exercise. Body composition (DEXA), muscular performance (1-RM bench press and repetitions to failure [RTF: 3 sets × baseline body weight, 60-sec rest between sets]), and clinical blood chemistries were measured at baseline and after nine weeks of supplementation and training. Subjects were required to maintain their normal dietary habits and follow a specific, progressive overload resistance training program (4-days/wk, upper body/lower body split) during the study. An intent-to-treat approach was used and data were analyzed via ANCOVA using baseline values as the covariate. Statistical significance was set a priori at p ≤ 0.05.
When adjusted for initial differences, significant between group post-test means were noted in: 1-RM bench press (SOmaxP: 133.3 ± 1.3 kg [19.8% increase] vs. CP: 128.5 ± 1.3 kg [15.3% increase]; p < 0.019); lean mass (SOmaxP: 64.1 ± 0.4 kg [2.4% increase] vs. 62.8 ± 0.4 kg [0.27% increase], p < 0.049); RTF (SOmaxP: 33.3 ± 1.1 reps [44.8% increase] vs. 27.8 ± 1.1 reps [20.9% increase], p < 0.004); and fat mass (SOmaxP: 12.06 ± 0.53 kg [9.8% decrease] vs. 13.90 ± 0.53 kg [4.1% increase], p < 0.024). No statistically significant differences in vital signs (heart rate, systolic and diastolic blood pressures) or clinical blood chemistries were noted.
These data indicate that compared to CP, SOmaxP administration augments and increases gains in lean mass, bench press strength, and muscular performance during nine weeks of intense resistance training. Studies designed to confirm these results and clarify the molecular mechanisms by which SOmaxP exerts the observed salutary effects have begun. Both SOmaxP and the CP were well-tolerated, and no supplement safety issues were identified.
本研究旨在比较补充 Gaspari Nutrition 的 SOmaxP Maximum Performance™（SOmaxP）与含有等量肌酸（4 克）、碳水化合物（39 克麦芽糊精）和蛋白质（7 克乳清蛋白水解物）的对照产品（CP）对肌肉力量、肌肉耐力和身体成分的影响在九周的高强度抗阻训练中。
采用前瞻性、随机、双盲设计，20 名健康男性（平均±SD 年龄、身高、体重、体脂率：22.9±2.6 岁、178.4±5.7cm、80.5±6.6kg、16.6±4.0%）按年龄、体重、抗阻训练史、卧推强度、卧推耐力和体脂率进行匹配，然后通过 ABBA 程序随机分配，在抗阻运动前和运动中各服用 1/2 勺（溶解在 15 盎司水中）SOmaxP 或 CP。在补充和训练九周后测量身体成分（DEXA）、肌肉表现（1-RM 卧推和重复至力竭[RTF：3 组×基线体重，组间休息 60 秒]）和临床血液化学。在研究期间，受试者被要求保持正常的饮食习惯，并遵循特定的、渐进的抗阻训练计划（4 天/周，上半身/下半身分开）。采用意向治疗方法，使用协方差分析（将基线值作为协变量）进行数据分析。预先设定统计显著性为 p≤0.05。
当调整初始差异后，两组间的测试后平均值有显著差异：1-RM 卧推（SOmaxP：133.3±1.3kg[19.8%增加]vs.CP：128.5±1.3kg[15.3%增加]；p<0.019）；瘦体重（SOmaxP：64.1±0.4kg[2.4%增加]vs.62.8±0.4kg[0.27%增加]；p<0.049）；RTF（SOmaxP：33.3±1.1 次[44.8%增加]vs.27.8±1.1 次[20.9%增加]；p<0.004）；和脂肪量（SOmaxP：12.06±0.53kg[9.8%减少]vs.13.90±0.53kg[4.1%增加]；p<0.024）。未观察到生命体征（心率、收缩压和舒张压）或临床血液化学的统计学差异。
这些数据表明，与 CP 相比，SOmaxP 可增强和增加九周高强度抗阻训练期间的瘦体重、卧推力量和肌肉表现的增加。已开始设计研究以确认这些结果并阐明 SOmaxP 发挥观察到的有益效果的分子机制。SOmaxP 和 CP 均耐受良好，未发现补充剂安全性问题。
