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酷似神经源性肿瘤的腰椎脊索瘤。

Lumbar chordoma mimicking a neurogenic tumour.

机构信息

Department of Neurosurgery, Level 4, Block C, Wollongong Hospital, Loftus Street, Wollongong, New South Wales 2500, Australia.

出版信息

J Clin Neurosci. 2011 Feb;18(2):302-4. doi: 10.1016/j.jocn.2010.07.098. Epub 2010 Dec 15.

Abstract

Chordomas are rare tumours arising from the primitive notochord along the axial skeleton, typically from the sacrococcygeal region, spheno-occipital region and less commonly, the mobile spine. Midline location associated with bony involvement with extension to the surrounding tissues is the norm. Chordomas presenting laterally, centred within the neural exit foramen and extending to the paraspinal muscles without significant vertebral involvement is rare. We present a 60-year-old woman with lower back pain and radiculopathy. Imaging revealed a unilateral lesion at L4/5 extending through the left neural exit foramen into the paraspinal region. There was only minimal apparent bony involvement. Though these features were highly suggestive of a neurogenic tumour, histopathology revealed the lesion to be a chordoma. Excision of the tumour was performed under neurophysiological monitoring.

摘要

脊索瘤是一种罕见的肿瘤,起源于沿轴骨骼的原始脊索,通常来自骶尾部、蝶枕部,较少见于活动脊柱。中线位置伴有骨受累并延伸至周围组织是其特征。侧向出现、位于神经出口孔中央并延伸至椎旁肌肉而无明显椎体受累的脊索瘤较为罕见。我们报告一例 60 岁女性,表现为腰痛和神经根病。影像学检查显示 L4/5 单侧病变,穿过左侧神经出口孔进入椎旁区域。只有轻微的明显骨受累。尽管这些特征高度提示为神经源性肿瘤,但组织病理学显示病变为脊索瘤。在神经生理监测下进行了肿瘤切除术。

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