Department of Internal Medicine, Mitochondrial Research Group Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
J Korean Med Sci. 2010 Dec;25(12):1777-83. doi: 10.3346/jkms.2010.25.12.1777. Epub 2010 Nov 24.
The purpose of this study was to examine the urban-rural differences in the prevalence and associated factors with type 2 diabetes mellitus (T2DM) in Korean adults. A total of 1,060 adults >30 yr of age from urban (189 males and 331 females) and rural districts (219 males and 321 females) were recruited. Anthropometric measures, blood pressure, lipid profiles, and fasting and 2-hr after 75-g oral glucose load blood glucose were obtained. The crude- and age-standardized prevalence of T2DM was 15.4% and 14.5%, and 11.7% and 8.6% in urban and rural districts, respectively. Diabetic subjects were older and obese, and had a higher triglyceride level, and systolic blood pressure compared to non-diabetes in both population. Multivariate regression analysis revealed that older age, high triglyceride levels, central obesity, and hypertension were significantly associated with T2DM in both areas. Low monthly incomes were significantly associated with T2DM in urban population, while a family history of T2DM was significantly associated with T2DM in rural area. T2DM is more prevalent in urban than in rural population, and low economic status or genetic factor is differently associated with T2DM in both population, respectively.
本研究旨在探讨韩国成年人中 2 型糖尿病（T2DM）的城乡患病率及其相关因素。共招募了来自城市（189 名男性和 331 名女性）和农村地区（219 名男性和 321 名女性）的 1060 名年龄在 30 岁以上的成年人。测量了人体测量指标、血压、血脂谱以及空腹和口服 75g 葡萄糖后 2 小时的血糖。T2DM 的粗患病率和年龄标准化患病率分别为 15.4%和 14.5%，城市和农村地区分别为 11.7%和 8.6%。与非糖尿病患者相比，糖尿病患者年龄更大、肥胖、甘油三酯水平更高、收缩压更高。多变量回归分析显示，在两个地区，年龄较大、甘油三酯水平较高、中心性肥胖和高血压与 T2DM 显著相关。在城市人群中，月收入较低与 T2DM 显著相关，而在农村地区，T2DM 的家族史与 T2DM 显著相关。T2DM 在城市人群中比在农村人群中更为普遍，而在两个地区，经济地位较低或遗传因素与 T2DM 的相关性也不同。
