疟疾：对发病机制和抗疟药物的当前研究状况的评估。
Malaria: an evaluation of the current state of research on pathogenesis and antimalarial drugs.
机构信息
Graduate School of Arts & Sciences, Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA.
出版信息
Yale J Biol Med. 2010 Dec;83(4):185-91.
Abstract
This brief review provides an overview of the pathogenesis of malaria, the human immune response to malaria, current methodology for malaria diagnosis, and current antimalarial drug regimens. The review also provides a critical evaluation of the research directions in the areas of drug design and vaccine design.
摘要
本文简要综述了疟疾的发病机制、人体对疟疾的免疫反应、当前疟疾诊断方法以及当前抗疟药物方案。本文还对药物设计和疫苗设计领域的研究方向进行了批判性评估。
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Ecology: A world without mosquitoes.生态学：一个没有蚊子的世界。
Nature. 2010 Jul 22;466(7305):432-4. doi: 10.1038/466432a.
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Mitochondrial DNA targets increase sensitivity of malaria detection using loop-mediated isothermal amplification.环介导等温扩增技术中靶向线粒体 DNA 可提高疟疾检测的灵敏度。
J Clin Microbiol. 2010 Aug;48(8):2866-71. doi: 10.1128/JCM.00355-10. Epub 2010 Jun 16.
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