[A specific protein inhibiting membrane permeation of chloramphenicol in Pseudomonas aeruginosa].
作者信息
O'Hara K, Fukuda H, Kanda T, Kono M
机构信息
Department of Microbiology, Tokyo College of Pharmacy.
出版信息
Jpn J Antibiot. 1990 Apr;43(4):754-6.
PMID:2116539
Abstract
A specific protein (MW 18,000) was found using chloramphenicol (CP) base-affinity chromatography of periplasmic-space proteins obtained from an impermeability-type CP-resistant Pseudomonas aeruginosa harboring plasmid kR102. Membrane reconstitution experiments using a liposome system appeared to indicate that the permeability of CP was inhibited by the specific protein.
摘要
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