Durnian Jonathan M, Owen Manon E, Baddon Andrew C, Noonan Carmel P, Marsh Ian B
St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, UK.
J AAPOS. 2010 Dec;14(6):469-71. doi: 10.1016/j.jaapos.2010.08.013.
The introduction of the AS-20 strabismus-specific quality-of-life questionnaire allows clinicians to quantify the effects of strabismus on adults for the first time. We correlated strabismic patients' demographic and clinical findings to their AS-20 scores.
A consecutive cohort of patients from an ongoing prospective study of adults with manifest strabismus was recruited. The patients' age, sex, socioeconomic status (SES), magnitude, and direction of deviation were correlated to their AS-20 scores. Patients' zip codes were used to derive a score for their SES based on the English 2007 Index of Multiple Deprivation score (IMD2007).
A total of 61 questionnaires with all demographic and clinical data were available. The median magnitude of deviation was 20.4(Δ) in this group. The mean AS-20 score was 49.5 (SD 21.6). Women had significantly lower AS-20 scores than men (p = 0.02). There was no difference in AS-20 scores between individuals with eso- and exodeviations (p = 0.7). Multiple linear regression analysis shows female sex and lower SES to be significantly associated with lower AS-20 scores (p = 0.03 and p = 0.006, respectively).
Strabismic patients who are female or live in a more deprived area have a significantly lower AS-20 score.
AS - 20斜视特异性生活质量问卷的引入，首次使临床医生能够量化斜视对成年人的影响。我们将斜视患者的人口统计学和临床特征与其AS - 20评分进行了关联分析。
从一项正在进行的成人显性斜视前瞻性研究中连续招募患者队列。将患者的年龄、性别、社会经济地位（SES）、斜视度数和斜视方向与其AS - 20评分进行关联分析。根据2007年英国多重贫困指数评分（IMD2007），利用患者的邮政编码得出其SES评分。
共有61份包含所有人口统计学和临床数据的问卷。该组患者斜视度数的中位数为20.4（Δ）。AS - 20评分的平均值为49.5（标准差21.6）。女性的AS - 20评分显著低于男性（p = 0.02）。内斜视和外斜视患者的AS - 20评分无差异（p = 0.7）。多元线性回归分析显示，女性和较低的SES与较低的AS - 20评分显著相关（分别为p = 0.03和p = 0.006）。
女性或生活在贫困地区的斜视患者AS - 20评分显著较低。
