Department of Urology, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois 60153, USA.
J Urol. 2011 Feb;185(2):605-9. doi: 10.1016/j.juro.2010.09.098. Epub 2010 Dec 18.
With the now routine use of computerized tomography angiography with 3-dimensional reconstruction in the donor evaluation, renal volume can be easily determined using volume calculating software. We evaluated whether donor renal volume could predict recipient renal function.
Clinical data of all donor and recipient pairs undergoing live donor kidney transplantation at our institution between January 2006 and October 2009 were reviewed. The volume of the kidney selected for transplant was determined using volume calculating software, and correlated to transplant recipient nadir and 1-year serum creatinine. Multivariate regression analysis was performed to adjust for demographic and clinical variables.
During the study period 114 patients underwent live donor renal transplantation. Recipient nadir and 1-year serum creatinine levels were significantly correlated with the volume of donated kidney even after adjusting for age, body mass index, body surface area and donor creatinine clearance. Kidney volume also retained significance after excluding recipients from analysis who experienced acute rejection episodes.
Larger kidney volumes calculated using 3-dimensional computerized tomography with volume calculating software are correlated with lower recipient nadir and 1-year serum creatinine levels.
随着计算机断层血管造影术（CTA）三维重建在供者评估中的常规应用，使用体积计算软件可以轻松地确定肾脏体积。我们评估了供者肾脏体积是否可以预测受者肾功能。
回顾了 2006 年 1 月至 2009 年 10 月期间在我们机构接受活体供肾移植的所有供者和受者对的临床数据。使用体积计算软件确定选定用于移植的肾脏的体积，并与移植受者的最低值和 1 年血清肌酐相关联。进行多变量回归分析以调整人口统计学和临床变量。
在研究期间，114 名患者接受了活体供肾移植。即使在调整了年龄、体重指数、体表面积和供者肌酐清除率后，受者的最低值和 1 年血清肌酐水平仍与捐赠肾脏的体积显著相关。在排除了经历急性排斥反应的受者的分析后，肾脏体积仍然具有显著性。
使用体积计算软件的三维 CT 计算出的较大的肾脏体积与较低的受者最低值和 1 年血清肌酐水平相关。
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