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Degradable, thermo-sensitive poly(N-isopropyl acrylamide)-based scaffolds with controlled porosity for tissue engineering applications.可降解、温敏性聚(N-异丙基丙烯酰胺)基多孔支架在组织工程中的应用。
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Epidermal and dermal integration into sphere-templated porous poly(2-hydroxyethyl methacrylate) implants in mice.表皮和真皮整合到球体模板化多孔聚(2-羟乙基甲基丙烯酸酯)植入物中在小鼠体内。
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"Smart" diblock copolymers as templates for magnetic-core gold-shell nanoparticle synthesis.“智能”两亲嵌段共聚物作为核壳型金磁纳米粒子合成的模板。
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2010 生物材料大挑战专家组

2010 Panel on the biomaterials grand challenges.

机构信息

Department of Biomedical Engineering, Duke University, Durham, North Carolina, USA.

出版信息

J Biomed Mater Res A. 2011 Feb;96(2):275-87. doi: 10.1002/jbm.a.32969. Epub 2010 Nov 29.

DOI:10.1002/jbm.a.32969
PMID:21171147
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4076103/
Abstract

In 2009, the National Academy for Engineering issued the Grand Challenges for Engineering in the 21st Century comprised of 14 technical challenges that must be addressed to build a healthy, profitable, sustainable, and secure global community (http://www.engineeringchallenges.org). Although crucial, none of the NEA Grand Challenges adequately addressed the challenges that face the biomaterials community. In response to the NAE Grand Challenges, Monty Reichert of Duke University organized a panel entitled Grand Challenges in Biomaterials at the at the 2010 Society for Biomaterials Annual Meeting in Seattle. Six members of the National Academies-Buddy Ratner, James Anderson, Allan Hoffman, Art Coury, Cato Laurencin, and David Tirrell-were asked to propose a grand challenge to the audience that, if met, would significantly impact the future of biomaterials and medical devices. Successfully meeting these challenges will speed the 60-plus year transition from commodity, off-the-shelf biomaterials to bioengineered chemistries, and biomaterial devices that will significantly advance our ability to address patient needs and also to create new market opportunities.

摘要

2009 年,美国国家工程院发布了 21 世纪的 14 项重大工程挑战,其中包括必须解决的 14 项技术挑战,以建立一个健康、盈利、可持续和安全的全球社区(http://www.engineeringchallenges.org)。尽管这些挑战至关重要,但 NEA 重大挑战中没有一个充分解决生物材料界面临的挑战。针对 NAE 重大挑战,杜克大学的蒙蒂·赖克特(Monty Reichert)在 2010 年西雅图举行的生物材料学会年会上组织了一个题为“生物材料重大挑战”的小组讨论。要求美国国家科学院的六位成员——巴迪·拉特纳(Buddy Ratner)、詹姆斯·安德森(James Anderson)、艾伦·霍夫曼(Allan Hoffman)、阿特·库里(Art Coury)、卡托·劳伦森(Cato Laurencin)和大卫·蒂雷尔(David Tirrell)——向观众提出一个重大挑战,如果能够实现,将对生物材料和医疗器械的未来产生重大影响。成功应对这些挑战将加速 60 多年来从商品、现成的生物材料向生物工程化学和生物材料设备的过渡,这将显著提高我们满足患者需求的能力,并创造新的市场机会。