Laurencin Cato T, Nair Lakshmi S
Department of Orthopaedic Surgery; Institute for Regenerative Engineering; Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences; University of Connecticut Health Center, Farmington, CT 06030, USA; Department of Biomedical Engineering; Department of Materials Science and Engineering, Storrs, CT 06269, USA; Department of Chemical and Biomolecular Engineering University of Connecticut, Storrs, CT 06269, USA.
Department of Orthopaedic Surgery; Institute for Regenerative Engineering; Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences; University of Connecticut Health Center, Farmington, CT 06030, USA; Department of Biomedical Engineering; Department of Materials Science and Engineering, Storrs, CT 06269, USA.
Regen Eng Transl Med. 2015 Apr 1;1(1):1-3. doi: 10.1007/s40883-015-0006-z. Epub 2015 Dec 4.
The clinical grand challenge to regenerate complex tissue and organ systems call for a paradigm shift that requires a transdisciplinary approach. The field of regenerative engineering puts forward a Convergence approach to create a regenerative toolbox to move beyond individual tissue repair to the regeneration of complex tissues and organ systems. Here we discuss the regenerative tool box currently under development to address grand opportunities in complex tissue/organ regeneration.
再生复杂组织和器官系统所面临的临床重大挑战需要一种范式转变，这需要跨学科方法。再生工程领域提出了一种融合方法，以创建一个再生工具箱，从而超越个体组织修复，实现复杂组织和器官系统的再生。在此，我们讨论目前正在开发的再生工具箱，以应对复杂组织/器官再生中的重大机遇。
