Ai Ling, Liu Si-yao, Huang Jun, Chen Shao-wei, Liu Jing, Zhong Ying
Reproductive Medicine Center, Jinjiang Maternal and Child Health Hospital, Chengdu, Sichuan 610051, China.
Zhonghua Nan Ke Xue. 2010 Sep;16(9):826-9.
To assess whether intracytoplasmic morphologically selected sperm injection (IMSI) of testicular sperm improves the clinical outcome in patients with azoospermia.
We performed conventional intracytoplasmic sperm injection (ICSI) for 66 patients diagnosed with azoospermia and IMSI for another 39 using testicular sperm selected at high magnification ( x 6000), and comparatively analyzed the clinical outcomes of the two techniques.
There were no statistically significant differences between conventional ICSI and IMSI in the rates of pregnancy (51.52% vs. 56.41%) and implantation (30.67% vs. 35.29%), although the rate of early abortion was lower in the IMSI than in the ICSI group (4.50% vs. 11.76%).
IMSI of testicular sperm may effect a lower rate of early abortion than conventional ICSI in patients with azoospermia.
评估睾丸精子的胞浆内形态学选择精子注射（IMSI）是否能改善无精子症患者的临床结局。
我们对66例诊断为无精子症的患者进行了常规胞浆内精子注射（ICSI），并对另外39例患者使用高倍镜（×6000）选择的睾丸精子进行了IMSI，比较分析了两种技术的临床结局。
常规ICSI和IMSI在妊娠率（51.52%对56.41%）和着床率（30.67%对35.29%）方面无统计学显著差异，尽管IMSI组的早期流产率低于ICSI组（4.50%对11.76%）。
在无精子症患者中，睾丸精子的IMSI可能比常规ICSI导致更低的早期流产率。
