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因溃疡性结肠炎导致的横结肠和乙状结肠扭转而出现非毒性巨结肠。

Non-toxic megacolon due to transverse and sigmoid colon volvulus in a patient with ulcerative colitis.

机构信息

1st Department of Internal Medicine & Hepato-Gastroenterology Unit, Medical School, University of Ioannina, 451 10 Ioannina, Greece.

出版信息

J Crohns Colitis. 2009 Feb;3(1):38-41. doi: 10.1016/j.crohns.2008.09.002. Epub 2008 Oct 26.

Abstract

Intestinal volvulus in patients with inflammatory bowel disease is rare. A 83-year-old woman diagnosed with ulcerative colitis five years ago was referred to our hospital due to abdominal distension. The patient had been diagnosed with pancolitis and dolichocolon and was started on mesalazine 1.5 g/day treatment resulting in long-term remission. Physical examination showed abdominal distention with no rebound; however on auscultation abdominal sounds were absent. Patient had no signs of toxicity. Temperature was 38.2 °C, heart rate was 82 bpm and respirations were 16/min. Laboratory investigation showed elevated white blood cell count (20,000/mm(3)) with hemoglobin at 13.2 g/dl and C-reactive protein at 310 mg/dl. Radiology was suggestive of megacolon and volvulus. Patient underwent endoscopy, which revealed normal rectal mucosa; there were however present areas of bowel gangrene. Urgent laparotomy was performed which revealed double transverse and sigmoid colon volvulus. A left hemicolectomy and transversectomy were performed. A case of a patient with ulcerative colitis is being presented here, exhibiting a non-toxic megacolon, resulting from a double transverse and sigmoid volvulus probably stemming from congenital dolichocolon. This case is stressing the importance of prompt differential diagnosis in such cases of megacolon as any symptom misinterpretation may result in unfavorable outcomes.

摘要

炎症性肠病患者的肠扭转较为罕见。一位 83 岁女性,五年前被诊断为溃疡性结肠炎,因腹胀来我院就诊。该患者被诊断为全结肠炎和长结肠,并开始每天服用美沙拉嗪 1.5 g,病情长期缓解。体格检查显示腹胀,无反弹;但听诊时腹部无肠鸣音。患者无中毒迹象。体温为 38.2°C,心率为 82 次/分,呼吸为 16 次/分。实验室检查显示白细胞计数升高(20,000/mm³),血红蛋白为 13.2 g/dl,C 反应蛋白为 310 mg/dl。影像学检查提示巨结肠和扭转。患者接受了内镜检查,显示直肠黏膜正常;但存在肠坏死区域。紧急剖腹手术发现横结肠和乙状结肠双重扭转。进行了左半结肠切除术和横结肠切除术。本文报告了一例溃疡性结肠炎患者,表现为非中毒性巨结肠,由双重横结肠和乙状结肠扭转引起,可能源于先天性长结肠。该病例强调了在这种巨结肠情况下及时进行鉴别诊断的重要性,因为任何症状的误解都可能导致不良后果。

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