Department of Neurology, Adult Epilepsy Center, The University of Chicago, Chicago, IL 60637, USA.
Epilepsia. 2010 Nov;51(11):2344-7. doi: 10.1111/j.1528-1167.2010.02719.x. Epub 2010 Sep 24.
Sudden unexpected death in epilepsy (SUDEP) is the leading cause of mortality in patients with chronic uncontrolled epilepsy. Despite intense interest in SUDEP from the medical and scientific communities in recent years, its etiologies are still largely unresolved. A 35-year-old woman had SUDEP after having a generalized seizure in the prone position. The cause of her death was likely asphyxia from the convergence of postictal coma and suspected positional airway obstruction and hypoventilation, rather than the commonly suspected periictal cardiac arrhythmia or central apnea. SUDEP may share a similar etiology with sudden infant death syndrome (SIDS) and is likely preventable, at least in a proportion of cases.
癫痫性猝死（SUDEP）是慢性、未经控制的癫痫患者死亡的主要原因。尽管近年来医学和科学界对 SUDEP 产生了浓厚的兴趣，但它的病因仍在很大程度上尚未得到解决。一名 35 岁女性在俯卧位癫痫发作后发生 SUDEP。她的死亡原因可能是癫痫后昏迷与可疑的体位性气道阻塞和通气不足导致的窒息，而不是常见的怀疑与癫痫发作相关的心律失常或中枢性呼吸暂停。SUDEP 可能与婴儿猝死综合征（SIDS）具有相似的病因，并且至少在一定比例的病例中是可以预防的。
