Department of Epidemiology, Southern Medical University, Guangzhou, China.
BMC Public Health. 2010 Dec 22;10:780. doi: 10.1186/1471-2458-10-780.
China has experienced an increase in the prevalence of childhood overweight/obesity over the last decades. The purpose of this study was to examine the prevalence of obesity and metabolic syndrome among Chinese school children and determine if there is a significant association between childhood obesity and metabolic syndrome.
A cross-sectional study was conducted among 1844 children (938 males and 906 females) in six elementary schools at Guangzhou city from April to June 2009. The body mass index (BMI), waist circumference, blood pressure, Tanner stage, lipids, insulin and glucose levels were determined. Criteria analogous to ATPIII were used for diagnosis of metabolic syndrome in children.
Among 1844 children aged 7-14 years, 205 (11.1%) were overweight, and 133 (7.2%) were obese. The prevalence of metabolic syndrome was 6.6% overall, 33.1% in obese, 20.5% in overweight and 2.3% in normal weight children. Multiple logistic regression analysis showed that BMI (3rd quartile)(OR 3.28; 95%CI 0.35-30.56), BMI (4th quartile)(OR 17.98; 95%CI 1.75-184.34), homeostasis model assessment (HOMA-IR) (2nd quartile) (OR2.36; 95% CI 0.46-12.09), HOMA-IR (3rd quartile) (OR 2.46; 95% CI 0.48-12.66), HOMA-IR (4th quartile) (OR3.87; 95% CI 0.72-20.71) were significantly associated with metabolic syndrome.
The current epidemic of obesity with subsequent increasing cardiovascular risk factors has constituted a threat to the health of school children in China. HOMA-IR and BMI were strong predictors of metabolic syndrome in children. Therefore, rigorous obesity prevention programs should be implemented among them.
过去几十年，中国儿童超重/肥胖的患病率有所上升。本研究旨在调查中国学童肥胖和代谢综合征的患病率，并确定儿童肥胖与代谢综合征之间是否存在显著关联。
2009 年 4 月至 6 月，在广州市六所小学的 1844 名儿童（男 938 名，女 906 名）中进行了横断面研究。测定了体重指数（BMI）、腰围、血压、Tanner 分期、血脂、胰岛素和血糖水平。采用 ATPIII 标准诊断儿童代谢综合征。
在 1844 名 7-14 岁的儿童中，205 名（11.1%）超重，133 名（7.2%）肥胖。代谢综合征的总患病率为 6.6%，肥胖儿童为 33.1%，超重儿童为 20.5%，正常体重儿童为 2.3%。多因素 logistic 回归分析显示，BMI（第 3 四分位）（OR3.28；95%CI0.35-30.56）、BMI（第 4 四分位）（OR17.98；95%CI1.75-184.34）、稳态模型评估（HOMA-IR）（第 2 四分位）（OR2.36；95%CI0.46-12.09）、HOMA-IR（第 3 四分位）（OR2.46；95%CI0.48-12.66）、HOMA-IR（第 4 四分位）（OR3.87；95%CI0.72-20.71）与代谢综合征显著相关。
目前肥胖流行，随后心血管危险因素增加，对中国学童健康构成威胁。HOMA-IR 和 BMI 是儿童代谢综合征的强有力预测因子。因此，应在儿童中实施严格的肥胖预防计划。
