Blood Systems Research Institute, San Francisco, CA 94118, USA.
J Gen Virol. 2011 Apr;92(Pt 4):768-72. doi: 10.1099/vir.0.028704-0. Epub 2010 Dec 22.
Circoviruses consist of highly prevalent and genetically diverse porcine and avian pathogens. The genomes of cycloviruses, a proposed new genus in the family Circoviridae, were recently identified in human and chimpanzee faeces. Here, six cyclovirus and four circovirus genomes from the tissues of chickens, goats, cows, and a bat were amplified and sequenced using rolling-circle amplification and inverse PCR. A goat cyclovirus was nearly identical to a cyclovirus from a cow. USA beef contained circoviruses with >99% similarity to porcine circovirus 2b. Circoviruses in chicken were related to those of pigeons. The close genetic similarity of a subset of cycloviruses and circoviruses replicating in distinct animal species may reflect recent cross-species transmissions. Further studies will be required to determine the impact of these highly prevalent infections on the health of farm animals.
圆环病毒属于圆环病毒科，由高度流行和遗传多样的猪和禽病原体组成。最近在人类和黑猩猩粪便中发现了圆环病毒，这是一个拟议的新属。本研究采用滚环扩增和反向 PCR 技术，从鸡、山羊、牛和蝙蝠的组织中扩增和测序了 6 种圆环病毒和 4 种圆环病毒基因组。一种山羊圆环病毒与牛圆环病毒非常相似。美国牛肉中含有与猪圆环病毒 2b 相似度>99%的圆环病毒。鸡圆环病毒与鸽子圆环病毒有关。在不同动物物种中复制的一组圆环病毒和圆环病毒的密切遗传相似性可能反映了最近的跨物种传播。需要进一步研究这些高度流行的感染对农场动物健康的影响。
