Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences Key Laboratory of Animal Diseases, Diagnostics, and Immunology, Ministry of Agriculture National Center for Engineering Research of Veterinary Bio-products, Nanjing, Jiangsu, China.
Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infections Diseases and Zoonoses, Yangzhou, Jiangsu, China.
Transbound Emerg Dis. 2018 Feb;65(1):e217-e218. doi: 10.1111/tbed.12716. Epub 2017 Sep 21.
Porcine circovirus-like virus P1, a novel single-stranded circular DNA virus, is a potential causative agent of post-weaning multisystemic wasting syndrome in swine. In this study, we detected P1 strains in serum samples from cattle, goats and rabbits suffering different clinical symptoms, in Jiangsu Province, China. We sequenced the whole genomes of six P1 strains, which showed 99.4%-100% nucleotide sequence similarity and were closely related to other porcine-origin P1 isolates. The sequences of six non-porcine-origin P1 viruses were most closely phylogenetically related to other porcine-origin P1 sequences. Therefore, the P1 virus has a wide host range in China.
猪圆环病毒样病毒 P1 是一种新型单链环状 DNA 病毒，可能是引起猪断奶后多系统消耗综合征的病原体。本研究在中国江苏，从患有不同临床症状的牛、山羊和兔血清样本中检测到 P1 株。我们对 6 株 P1 全基因组进行了测序，其核苷酸序列相似性为 99.4%-100%，与其他猪源 P1 分离株密切相关。6 株非猪源 P1 病毒的序列与其他猪源 P1 序列的亲缘关系最密切。因此，P1 病毒在中国宿主范围广泛。
