Takahashi Y, Suga T, Ohta T, Sawaguchi K, Ogino T, Mai M
Dept. of Surgery, Kanazawa University.
Gan To Kagaku Ryoho. 1990 Aug;17(8 Pt 2):1754-7.
We have studied the effect of intraarteric infusion chemotherapy with missile chemotherapy, induced hypertensive chemotherapy and/or two-route infusion chemotherapy in 14 liver tumors (7 cases with liver metastasis from gastric cancer, 3 cases with liver metastasis from colonic cancer, 4 cases with hepatoma). Results indicated that PR in 6 (46.1%) out the 13 evaluated cases. The toxicity was not evident except for slight bone marrow depression with 5 cases and a low grade fever with 2 cases. These results indicate that intraarterial infusion chemotherapy with drug delivery system can be considered one of the treatment therapies available for a nonresectable tumor.
我们研究了在14例肝肿瘤（7例胃癌肝转移、3例结肠癌肝转移、4例肝癌）中采用导向化疗、诱导性高血压化疗和/或双途径灌注化疗进行动脉内灌注化疗的效果。结果显示，在13例可评估病例中，6例（46.1%）达到部分缓解。除5例出现轻微骨髓抑制和2例出现低热外，毒性不明显。这些结果表明，采用药物递送系统的动脉内灌注化疗可被视为不可切除肿瘤的可用治疗方法之一。
