Stop TB Department, World Health Organization, Geneva, Switzerland.
Int J Tuberc Lung Dis. 2010 Dec;14(12):1513-7.
The steadily growing epidemic of diabetes mellitus (DM) poses a threat for global tuberculosis (TB) control. Previous studies have identified an important association between DM and TB. However, these studies have limitations: very few were carried out in low-income countries, and none in Africa, raising uncertainty about the strength of the DM-TB association in these settings, and many critical questions remain unanswered. As a result of these questions and uncertainties, the International Union Against Tuberculosis and Lung Disease (The Union), the World Diabetes Foundation and the World Health Organization Stop TB Department undertook a series of consultations as of January 2009. A systematic review and meta-analysis was undertaken by the Department of Epidemiology, Harvard School of Public Health between May and August 2009, and a consultation meeting involving the experts who reviewed the report took place at The Union Headquarters in Paris on 6 and 7 November 2009. This paper constitutes a summary report of the findings, the research gaps and prioritised areas of research, and the recommendations from that meeting.
糖尿病(DM)的流行呈稳步上升趋势,这对全球结核病(TB)控制构成了威胁。之前的研究已经确定了 DM 和 TB 之间存在重要关联。然而,这些研究存在一些局限性:它们很少在低收入国家开展,而且在非洲也没有开展,这使得在这些环境中 DM-TB 关联的强度存在不确定性,并且仍有许多关键问题尚未得到解答。由于这些问题和不确定性,国际防痨和肺病联合会(The Union)、世界糖尿病基金会和世界卫生组织遏制结核病司于 2009 年 1 月开始进行了一系列磋商。哈佛大学公共卫生学院流行病学系于 2009 年 5 月至 8 月进行了系统评价和荟萃分析,2009 年 11 月 6 日至 7 日,在巴黎的 The Union 总部举行了一次咨询会议,参与报告评审的专家参加了会议。本文是该会议的总结报告,内容涉及研究结果、研究差距和优先研究领域,以及会议建议。