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尼日利亚一家教学医院中传统眼药的发病率及并发症

Incidence and complications of traditional eye medications in Nigeria in a teaching hospital.

作者信息

Ukponmwan Catherine U, Momoh Nanaiashat

机构信息

Department of Ophthalmology, University of Benin Teaching Hospital, Benin City, Nigeria.

出版信息

Middle East Afr J Ophthalmol. 2010 Oct;17(4):315-9. doi: 10.4103/0974-9233.71596.

Abstract

PURPOSE

The aim of this study was to determine the types and nature of traditional eye medications (TEMs), their sources, and the ocular complications that may arise from use in a teaching hospital in Nigeria.

MATERIALS AND METHODS

A prospective study of consecutive subjects who used TEM before presentation to the Eye Clinic of the University of Benin Teaching Hospital, Benin City, Nigeria between July 1, 2004 and June 30, 2008. P < 0.05 was considered statistically significant.

RESULTS

A total of 113 subjects were evaluated of which 64 were males (56.6%), females (43.4%) were females. There was no significant difference in the number of males and females (P > 0.05). Rural dwellers were more likely to use TEM than urban dwellers (P < 0.0001). The mean age of the subjects was 47.9 ± 22.3 years (range, 4-90 years). The most common traditional medication was derived from plant extracts (54.9%) followed by concoctions (21.2%). Complications occurred in 54.8% of the subjects. Ocular complications included corneal opacities in 13.35% of subjects, staphyloma in 9%, and corneal ulcers in 8%. Other complications were panophthalmitis, endophthalmitis, uveitis, cataract, and bullous keratopathy. Eleven subjects underwent evisceration or enucleation of the affected eye. There was no significant difference in the type of medication used and ocular complications (P = 0.956). Sources of TEM were self-medication in 38.9% of subjects, relatives in 27.4%, and traditional healers in 17.7%.

CONCLUSION

The use of TEM is a common practice that could be harmful and lead to blindness. Proper health education of the public and traditional healers can reduce the prevalence of preventable blindness.

摘要

目的

本研究旨在确定尼日利亚一家教学医院中传统眼药(TEMs)的类型和性质、其来源以及使用后可能出现的眼部并发症。

材料与方法

对2004年7月1日至2008年6月30日期间在尼日利亚贝宁城贝宁大学教学医院眼科诊所就诊前使用TEM的连续受试者进行前瞻性研究。P < 0.05被认为具有统计学意义。

结果

共评估了113名受试者,其中男性64名(56.6%),女性49名(43.4%)。男性和女性数量无显著差异(P > 0.05)。农村居民比城市居民更有可能使用TEM(P < 0.0001)。受试者的平均年龄为47.9 ± 22.3岁(范围为4 - 90岁)。最常见的传统药物来自植物提取物(54.9%),其次是混合药剂(21.2%)。54.8%的受试者出现并发症。眼部并发症包括13.35%的受试者出现角膜混浊、9%的受试者出现葡萄肿、8%的受试者出现角膜溃疡。其他并发症有全眼球炎、眼内炎、葡萄膜炎、白内障和大泡性角膜病变。11名受试者接受了患眼的眼球内容剜除术或眼球摘除术。所用药物类型与眼部并发症之间无显著差异(P = 0.956)。TEM的来源有38.9%的受试者为自我用药,27.4%为亲属提供,17.7%为传统治疗师提供。

结论

使用TEM是一种常见做法,但可能有害并导致失明。对公众和传统治疗师进行适当的健康教育可降低可预防失明的患病率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e515/2991448/94885a846698/MEAJO-17-315-g001.jpg

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