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Oral proton-pump inhibitors and step-down therapy for nonulcer dyspepsia: is this the right approach?口服质子泵抑制剂与非溃疡性消化不良的逐步降级治疗:这是正确的方法吗?
Therap Adv Gastroenterol. 2010 Mar;3(2):73-6. doi: 10.1177/1756283X09357220.
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本文引用的文献

1
Long-term safety concerns with proton pump inhibitors.质子泵抑制剂的长期安全性问题。
Am J Med. 2009 Oct;122(10):896-903. doi: 10.1016/j.amjmed.2009.04.014.
2
Proton-pump inhibitor therapy induces acid-related symptoms in healthy volunteers after withdrawal of therapy.质子泵抑制剂治疗停药后会在健康志愿者中诱发酸相关症状。
Gastroenterology. 2009 Jul;137(1):80-7, 87.e1. doi: 10.1053/j.gastro.2009.03.058. Epub 2009 Apr 10.
3
Effect and cost-effectiveness of step-up versus step-down treatment with antacids, H2-receptor antagonists, and proton pump inhibitors in patients with new onset dyspepsia (DIAMOND study): a primary-care-based randomised controlled trial.在新发消化不良患者中使用抗酸剂、H2受体拮抗剂和质子泵抑制剂进行逐步升级与逐步降级治疗的效果及成本效益(钻石研究):一项基于初级保健的随机对照试验
Lancet. 2009 Jan 17;373(9659):215-25. doi: 10.1016/S0140-6736(09)60070-2.
4
Meta-analysis: Helicobacter pylori'test and treat' compared with empirical acid suppression for managing dyspepsia.荟萃分析:幽门螺杆菌“检测与治疗”与经验性抑酸治疗消化不良的比较
Aliment Pharmacol Ther. 2008 Sep 1;28(5):534-44. doi: 10.1111/j.1365-2036.2008.03784.x. Epub 2008 Jun 27.
5
Randomized-controlled trial of esomeprazole in functional dyspepsia patients with epigastric pain or burning: does a 1-week trial of acid suppression predict symptom response?埃索美拉唑治疗伴有上腹部疼痛或烧灼感的功能性消化不良患者的随机对照试验:为期1周的抑酸试验能否预测症状反应?
Aliment Pharmacol Ther. 2007 Sep 1;26(5):673-82. doi: 10.1111/j.1365-2036.2007.03410.x.
6
Discontinuation of proton pump inhibitors in patients on long-term therapy: a double-blind, placebo-controlled trial.长期接受质子泵抑制剂治疗患者的停药研究:一项双盲、安慰剂对照试验
Aliment Pharmacol Ther. 2006 Sep 15;24(6):945-54. doi: 10.1111/j.1365-2036.2006.03084.x.
7
The functional gastrointestinal disorders and the Rome III process.功能性胃肠病与罗马Ⅲ标准制定过程
Gastroenterology. 2006 Apr;130(5):1377-90. doi: 10.1053/j.gastro.2006.03.008.
8
Eradication of Helicobacter pylori for non-ulcer dyspepsia.根除幽门螺杆菌治疗非溃疡性消化不良
Cochrane Database Syst Rev. 2006 Apr 19(2):CD002096. doi: 10.1002/14651858.CD002096.pub4.
9
Predictors of the placebo response in functional dyspepsia.功能性消化不良中安慰剂反应的预测因素。
Aliment Pharmacol Ther. 2006 Apr 1;23(7):923-36. doi: 10.1111/j.1365-2036.2006.02845.x.
10
Rebound acid hypersecretion after long-term inhibition of gastric acid secretion.长期抑制胃酸分泌后的胃酸分泌反跳性高分泌
Aliment Pharmacol Ther. 2005 Jan 15;21(2):149-54. doi: 10.1111/j.1365-2036.2004.02271.x.

Oral proton-pump inhibitors and step-down therapy for nonulcer dyspepsia: is this the right approach?

作者信息

Waldum Helge L, Martinsen Tom C, Hauso Oyvind, Qvigstad Gunnar

机构信息

Department of Gastroenterology and Liver Diseases, St Olav's Hospital HF, University Hospital of Trondheim; Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.

出版信息

Therap Adv Gastroenterol. 2010 Mar;3(2):73-6. doi: 10.1177/1756283X09357220.

DOI:10.1177/1756283X09357220
PMID:21180591
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3002572/
Abstract
摘要