消化不良的评估和管理。
Evaluation and management of dyspepsia.
机构信息
Digestive Health Center of Excellence, University of Virginia Medical Center, Box 800708, Charlottesville, VA 22908-0708.
出版信息
Therap Adv Gastroenterol. 2010 Mar;3(2):87-98. doi: 10.1177/1756283X09356590.
Abstract
Dyspepsia is a common clinical problem seen by both primary care physicians and gastroenterologists. Initial evaluation should focus on the identification and treatment of potential causes of symptoms such as gastroesophageal reflux disease (GERD), peptic ulcer disease, and medication side effects but also on recognizing those at risk for more serious conditions such as gastric cancer. This manuscript discusses the evaluation and management of dyspepsia including the role of proton-pump inhibitors, treatment of Helicobacter pylori, and endoscopy. Finally, treatment of refractory functional dyspepsia is addressed.
摘要
消化不良是基层医疗保健医生和胃肠病学家都常见的临床问题。初步评估应集中于识别和治疗症状的潜在原因，如胃食管反流病（GERD）、消化性溃疡病和药物副作用，同时还要识别那些有更严重疾病风险的患者，如胃癌。本文讨论了消化不良的评估和管理，包括质子泵抑制剂的作用、幽门螺杆菌的治疗和内镜检查。最后，还讨论了难治性功能性消化不良的治疗。
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Investigation of gastric emptying disorders in patients with functional dyspepsia reveals impaired inhibitory gastric emptying regulation in the early postcibal period.对功能性消化不良患者胃排空障碍的研究表明，在餐后早期抑制性胃排空调节受损。
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Is the antidepressant venlafaxine effective for the treatment of functional dyspepsia?抗抑郁药文拉法辛对功能性消化不良的治疗有效吗？
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Prevalence of celiac disease in adult patients with refractory functional dyspepsia: value of routine duodenal biopsy.难治性功能性消化不良成年患者中乳糜泻的患病率：常规十二指肠活检的价值
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Tegaserod treatment for dysmotility-like functional dyspepsia: results of two randomized, controlled trials.替加色罗治疗运动障碍样功能性消化不良：两项随机对照试验的结果
Am J Gastroenterol. 2008 Aug;103(8):1906-19. doi: 10.1111/j.1572-0241.2008.01953.x. Epub 2008 Jul 4.
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Meta-analysis: Helicobacter pylori'test and treat' compared with empirical acid suppression for managing dyspepsia.荟萃分析：幽门螺杆菌“检测与治疗”与经验性抑酸治疗消化不良的比较
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