Department of Oral Biosciences and Diagnosis, Univ Estadual Paulista, São José dos Campos, SP, Brazil.
Braz Oral Res. 2010 Oct-Dec;24(4):399-405. doi: 10.1590/s1806-83242010000400005.
A porous material for bone ingrowth with adequate pore structure and appropriate mechanical properties has long been sought as the ideal bone-implant interface. This study aimed to assess in vivo the influence of three types of porous titanium implant on the new bone ingrowth. The implants were produced by means of a powder metallurgy technique with different porosities and pore sizes: Group 1 = 30 % and 180 µm; Group 2 = 30% and 300 µm; and Group 3 = 40% and 180 µm;. Six rabbits received one implant of each type in the right and left tibiae and were sacrificed 8 weeks after surgery for histological and histomorphometric analyses. Histological analysis confirmed new bone in contact with the implant, formed in direction of pores. Histomorphometric evaluation demonstrated that the new bone formation was statistically significantly lower in the group G1 than in group G3, (P = 0.023). Based on these results, increased porosity and pore size were concluded to have a positive effect on the amount of bone ingrowth.
一种具有足够的孔结构和适当的机械性能的多孔材料，一直被视为理想的骨-植入物界面。本研究旨在评估三种类型的多孔钛植入物对新骨长入的体内影响。这些植入物是通过粉末冶金技术制造的，具有不同的孔隙率和孔径：第 1 组=30%和 180 µm；第 2 组=30%和 300 µm；第 3 组=40%和 180 µm。六只兔子的右侧和左侧胫骨分别植入了三种类型的植入物各一个，术后 8 周处死，进行组织学和组织形态计量学分析。组织学分析证实，植入物接触的新骨是沿孔方向形成的。组织形态计量学评估表明，第 G1 组的新骨形成明显低于第 G3 组（P=0.023）。基于这些结果，可以得出增加孔隙率和孔径对骨长入量有积极影响的结论。
