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以及对烧结多孔钛合金植入物的力学性能、生物相容性和成骨能力的评估。

and evaluations of mechanical properties, biocompatibility and osteogenic ability of sintered porous titanium alloy implant.

作者信息

Li Ji, Li Zhongli, Li Ruiling, Shi Yueyi, Wang Haoran, Wang Yuxing, Jin Gong

机构信息

Department of Orthopedics, General Hospital of PLA No. 28 Fuxing Road, Haidian District Beijing 100853 China

State Key Laboratory of Materials, Department of Materials Science and Engineering, Zhejiang University Hangzhou 310027 China.

出版信息

RSC Adv. 2018 Oct 29;8(64):36512-36520. doi: 10.1039/c8ra07518b. eCollection 2018 Oct 26.

Abstract

A new sintering technique using TiAlV powder suspension was performed to prepare porous TiAlV alloys. The porous alloys could be fabricated with different porosities and pore sizes by controlling the quantity and size of spacer particles added to the TiAlV powder. The characteristics and biological properties of the porous TiAlV with two different porosities were evaluated by mechanical tests, cell tests and implantation. Dense TiAlV was used as the control. Compared with the control group, the porous TiAlV showed good biocompatibility and osteogenic ability, which makes this type of porous alloy a good prospective material for biomedical application. And compared with 50% porosity, the alloy with 75% porosity had the optimal mechanical properties, and suitable pore size and porosity, which allowed more bone ingrowth.

摘要

采用一种使用TiAlV粉末悬浮液的新型烧结技术制备多孔TiAlV合金。通过控制添加到TiAlV粉末中的间隔颗粒的数量和尺寸,可以制造出具有不同孔隙率和孔径的多孔合金。通过力学测试、细胞测试和植入实验,对两种不同孔隙率的多孔TiAlV的特性和生物学性能进行了评估。致密TiAlV用作对照。与对照组相比,多孔TiAlV表现出良好的生物相容性和成骨能力,这使得这种类型的多孔合金成为生物医学应用的良好潜在材料。并且与50%孔隙率的合金相比,孔隙率为75%的合金具有最佳的力学性能、合适的孔径和孔隙率,能使更多的骨长入。

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