Policlinica Veterinaria y de Asesoría Zootécnica, Universidad Autónoma Metropolitana-Xochimilco, México D.F., Mexico.
Reprod Toxicol. 2011 May;31(4):570-3. doi: 10.1016/j.reprotox.2010.12.003. Epub 2010 Dec 21.
Boars fed on ration of 200 ppm Zn methionate showed a significant increase (P < 0.001) in sperm DNA fragmentation when compared to animals fed on non-supplemented and rations containing 150 ppm Zn methionate. There was a positive correlation (R2 = 0.207; P = 0.002) between % sperm DNA fragmentation (SDF) and the concentration of Zn in spermatozoa. Increased Zn in the diet also resulted in a non-proportional increase in Zn concentration in the testis and spermatozoa but not in the epididymis; Zn in sperm accumulated at levels up to 50 times higher than that found in the seminal plasma and 10-13 times that found in the epididymis and testis, respectively. These results show that supplementation of dietary Zn at a concentration of 200 ppm had an adverse effect on boar sperm DNA quality and may be related to the ability of spermatozoa to accumulate Zn during spermiogenesis.
当与未补充和含有 150ppm 蛋氨酸锌的日粮相比时，日粮中添加 200ppm 蛋氨酸锌的公猪的精子 DNA 碎片化显著增加（P<0.001）。精子 DNA 碎片化（SDF）的百分比与精子中锌的浓度之间存在正相关（R2=0.207；P=0.002）。饮食中增加锌也导致睾丸和精子中锌浓度的不成比例增加，但在附睾中没有增加；锌在精子中的积累水平高达比精液中高 50 倍，比附睾和睾丸中的分别高 10-13 倍。这些结果表明，日粮中添加 200ppm 的锌浓度对种公猪精子 DNA 质量有不良影响，这可能与精子在精子发生过程中积累锌的能力有关。
