Department of Neurology, Sanggye Paik Hospital, Inje University College of Medicine, 761-1, Sanggye 7 dong, No won gu, Seoul 139-707, Republic of Korea.
Parkinsonism Relat Disord. 2011 Mar;17(3):201-3. doi: 10.1016/j.parkreldis.2010.11.014. Epub 2010 Dec 23.
We aimed to investigate and compare sonographic abnormalities in the substantia nigra (SN) in patients with idiopathic restless legs syndrome (iRLS), those with RLS and Parkinson's disease (RLS-PD), those with idiopathic Parkinson's disease (iPD), and healthy controls. Study participants totaled 60 patients with RLS (41 iRLS, 19 RLS-PD), 25 iPD patients, and 35 age-matched healthy controls. Comparing all groups, the SN region's echogenicity area in the iRLS patients was significantly decreased compared with that in the PD-RLS, iPD, and control groups (p < 0.0001), and the PD-RLS group demonstrated a significantly increased echogenicity area compared with the control group (p < 0.05) and iRLS group (p < 0.0001). We found that the RLS-PD group's sonological results and clinical findings were different from those of the iRLS group.
我们旨在研究并比较特发性不安腿综合征（iRLS）、RLS 合并帕金森病（RLS-PD）、特发性帕金森病（iPD）患者及健康对照组患者黑质（SN）的超声异常。研究对象总计 60 例 RLS 患者（41 例 iRLS，19 例 RLS-PD）、25 例 iPD 患者和 35 名年龄匹配的健康对照组。将所有组进行比较，iRLS 患者的 SN 区域回声面积明显低于 PD-RLS、iPD 和对照组（p<0.0001），而 PD-RLS 组与对照组（p<0.05）和 iRLS 组（p<0.0001）相比回声面积明显增加。我们发现 RLS-PD 组的超声结果和临床发现与 iRLS 组不同。
