Maddah Mohsen, Sharami Seyede Hajar, Neyestani Tirang R
Department of Human Nutrition, School of Public Health, Guilan University of Medical Sciences, Rasht, I.R. Iran.
J Nutr Elder. 2009 Oct;28(4):386-93. doi: 10.1080/01639360903393523.
This study aimed to describe vitamin D status in postmenopausal women in urban and rural areas in Guilan, northern Iran. Between October 2004 and February 2005 a group of 750 women older than 50 years was randomly selected from urban and rural areas in Guilan. The participants were interviewed to collect data on age, educational level, body weight, height, employment status, reproductive history, medications, history of illness, and supplement use. Serum 25(OH) D was measured in 646 women (427 in urban areas and 219 women in rural areas). Serum 25(OH) D levels in urban and rural postmenopausal women were 18.5 ± 13.5 ng/ml and 22.9 ± 13.8 ng/ml (P < 0.0001), respectively. In urban and rural areas, 84.7% and 79.5% of the women had serum 25(OH) D levels less than 30 ng/ml, respectively. In this study, serum vitamin D levels and prevalence of vitamin D insufficiency was related to educational level in urban women. The urban women in the lowest educational level (<5 years schooling) had a better vitamin D status than other educational groups. This study showed that a high proportion of postmenopausal women living in Guilan province had vitamin D insufficiency. Vitamin D inadequacy was more common in urban areas and especially in the upper social class. Supplement use and national strategies to prevent vitamin D insufficiency are strongly needed in this community.
本研究旨在描述伊朗北部吉兰省城乡绝经后妇女的维生素D状况。2004年10月至2005年2月期间，从吉兰省城乡随机选取了一组750名50岁以上的女性。对参与者进行访谈，以收集有关年龄、教育程度、体重、身高、就业状况、生育史、用药情况、疾病史和补充剂使用情况的数据。对646名女性（城市地区427名，农村地区219名）测量了血清25(OH)D。城市和农村绝经后妇女的血清25(OH)D水平分别为18.5±13.5 ng/ml和22.9±13.8 ng/ml（P<0.0001）。在城市和农村地区，分别有84.7%和79.5%的女性血清25(OH)D水平低于30 ng/ml。在本研究中，城市女性的血清维生素D水平和维生素D不足患病率与教育程度有关。教育程度最低（<5年 schooling）的城市女性维生素D状况优于其他教育组。本研究表明，居住在吉兰省的绝经后妇女中很大一部分存在维生素D不足。维生素D不足在城市地区更为常见，尤其是在上层社会阶层。该社区强烈需要补充剂的使用和预防维生素D不足的国家策略。
