Department of Veterinary Clinical Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire, AL9 7TA, United Kingdom.
Vet Parasitol. 2011 May 31;178(1-2):100-7. doi: 10.1016/j.vetpar.2010.11.049. Epub 2010 Dec 7.
The prevalence of canine echinococcosis appears to have been increasing in mid/south Wales in recent years - raising the concern of a potential resurgence in transmission to humans. A campaign was therefore conducted in 2008 in order to provide dogs in South Powys with anthelmintics, estimate the coproantigen prevalence amongst these dogs, and evaluate potential risk factors for coproantigen positivity. The coproantigen prevalence identified in these dogs (n=577) was 10.6% (95% confidence interval 7.6-13.5%), with 20.6% (15.6-25.7%) of farms (n=247) containing at least one coproantigen-positive dog. Further spatial investigation identified considerable spatial heterogeneity amongst the farms, with an increased coproantigen prevalence in the regions of Brecknockshire and the Brecon Beacons National Park. Within these areas, there was strong evidence of an increase in coproantigen prevalence, compared to that found in a study conducted in 2002. Finally, a mixed effects logistic regression model identified increased roaming behaviour and decreased dog weight as being associated with increased odds of coproantigen positivity, whereas pet dogs on some farms had similar odds of infection to working dogs. Further surveillance efforts in South Powys are required and should also include the northern areas of Gwent and Glamorgan.
近年来，威尔士中部/南部的犬棘球蚴病发病率似乎呈上升趋势，这令人担忧其向人类传播的风险可能会再次增加。因此，2008 年开展了一项活动，为波伊斯南部的犬只提供驱虫药，估算这些犬只的粪抗原流行率，并评估粪抗原阳性的潜在风险因素。在这些犬只（n=577）中发现的粪抗原流行率为 10.6%（95%置信区间 7.6-13.5%），有 20.6%（15.6-25.7%）的农场（n=247）至少有一只粪抗原阳性犬。进一步的空间调查发现，农场之间存在相当大的空间异质性，布雷肯比肯斯国家公园和布雷肯郡地区的粪抗原流行率较高。在这些地区，与 2002 年进行的研究相比，粪抗原流行率有明显增加的证据。最后，混合效应逻辑回归模型确定，漫游行为增加和犬体重减轻与粪抗原阳性的几率增加有关，而一些农场的宠物犬与工作犬的感染几率相似。需要在波伊斯南部进行进一步的监测工作，还应包括格温特和格拉摩根北部地区。
