Department of Ophthalmology, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan.
Kaohsiung J Med Sci. 2010 Dec;26(12):673-8. doi: 10.1016/S1607-551X(10)70103-0.
In this study, we report a rare case of choroidal melanoma in an eye with oculodermal melanocytosis (Nevus of Ota). A 56-year-old Taiwanese woman with oculodermal melanocytosis in the right eye was found to have an ipsilateral uveal melanoma. Histopathology of the enucleated eye confirmed the diagnosis of malignant choroidal melanoma of mixed cell type. A search of the literature revealed strong evidence that oculodermal melanocytosis can predispose to the development of uveal melanoma in Caucasians. Only seven such cases have been reported in the East Asian population. This is believed to be the first such reported case in a patient of Chinese descent.
在这项研究中，我们报告了一例罕见的眼皮肤黑素细胞增多症（太田痣）合并脉络膜黑色素瘤病例。一名 56 岁的台湾女性右眼患有眼皮肤黑素细胞增多症，被发现同侧葡萄膜黑色素瘤。眼球摘除后的组织病理学检查证实了恶性混合细胞型脉络膜黑色素瘤的诊断。文献检索显示，强有力的证据表明眼皮肤黑素细胞增多症可使白种人易患葡萄膜黑色素瘤。在东亚人群中仅报道了 7 例此类病例。据信，这是首例报道的中国血统患者病例。
