Potapenko E I, Kochorova M N
Probl Tuberk. 1990(4):52-5.
To increase the effectiveness of diagnosing tuberculosis, a new procedure of defining B-rosette forming lymphocytes is proposed. A commercially available product, i.e. dry erythrocytic tuberculous phosphatidic diagnosticum produced by the Leningrad Vaccine and Serum Research Institute and meant for serologic examinations and antiphosphatidic antibody detection, was used in the above reaction for the first time. The following groups were selected for the examination: 51 patients with female genital, locomotor and ocular tuberculosis; 33 persons with nonspecific diseases of the same sites; and 19 donors. A significant drop in the absolute percentage of B-rosette forming lymphocytes (EAC-RFC-ph) in patients with active tuberculosis of all sites was found out. High diagnostic informativeness of the procedure is demonstrated. There was an inverse correlation between the level of antiphosphatidic antibodies and the content of B-rosette forming lymphocytes in tuberculosis patients and the examined controls.
为提高结核病的诊断效率，提出了一种定义B玫瑰花结形成淋巴细胞的新方法。首次在上述反应中使用了一种市售产品，即列宁格勒疫苗和血清研究所生产的用于血清学检查和抗磷脂抗体检测的干燥红细胞结核磷脂诊断试剂。选择以下几组进行检查：51例患有女性生殖、运动和眼部结核病的患者；33例患有相同部位非特异性疾病的人；以及19名献血者。发现所有部位活动性结核病患者中B玫瑰花结形成淋巴细胞（EAC-RFC-ph）的绝对百分比显著下降。该方法具有较高的诊断信息价值。结核病患者和受检对照中抗磷脂抗体水平与B玫瑰花结形成淋巴细胞含量之间呈负相关。
