嗜盐古菌沃氏嗜盐碱杆菌中色氨酸生物合成相关基因。
Genes for tryptophan biosynthesis in the archaebacterium Haloferax volcanii.
作者信息
Lam W L, Cohen A, Tsouluhas D, Doolittle W F
机构信息
Department of Biochemistry, Dalhousie University, Halifax, NS, Canada.
出版信息
Proc Natl Acad Sci U S A. 1990 Sep;87(17):6614-8. doi: 10.1073/pnas.87.17.6614.
Abstract
Recent technical advances permit direct genetic approaches for isolating genes and mapping auxotrophic mutations in the halophilic archaebacterium (Archaea) Haloferax volcanii. Twenty-nine mutations in tryptophan biosynthesis mapped to two separate chromosomal locations. DNA sequencing of one gene cluster shows a unique gene order (trpCBA) and unusual potential secondary structures in the 5'-flanking region.
摘要
最近的技术进展使得能够采用直接遗传学方法来分离嗜盐古细菌（古菌）沃氏嗜盐碱杆菌中的基因并定位营养缺陷型突变。色氨酸生物合成中的29个突变定位于两个不同的染色体位置。一个基因簇的DNA测序显示出独特的基因顺序（trpCBA）以及5'侧翼区域中不同寻常的潜在二级结构。
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