• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
A comprehensive sequence analysis program for the IBM personal computer.一款适用于IBM个人计算机的综合序列分析程序。
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):581-99. doi: 10.1093/nar/12.1part2.581.
2
DNA sequence analysis on the IBM-PC.在IBM个人电脑上进行DNA序列分析。
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):601-4. doi: 10.1093/nar/12.1part2.601.
3
Interactive computer programs for the graphic analysis of nucleotide sequence data.用于核苷酸序列数据图形分析的交互式计算机程序。
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):665-73. doi: 10.1093/nar/12.1part2.665.
4
A DNA sequence analysis package for the IBM personal computer.一款用于IBM个人计算机的DNA序列分析软件包。
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):605-14. doi: 10.1093/nar/12.1part2.605.
5
Microcomputer programs for graphic analysis of nucleic acid and protein sequences.用于核酸和蛋白质序列图形分析的微机程序。
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):811-7. doi: 10.1093/nar/12.1part2.811.
6
Apple II PASCAL programs for molecular biologists.面向分子生物学家的苹果II Pascal程序。
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):569-79. doi: 10.1093/nar/12.1part2.569.
7
A collection of programs for nucleic acid and protein analysis, written in FORTRAN 77 for IBM-PC compatible microcomputers.一套用于核酸和蛋白质分析的程序，用FORTRAN 77编写，适用于与IBM-PC兼容的微型计算机。
Nucleic Acids Res. 1986 Jan 10;14(1):455-65. doi: 10.1093/nar/14.1.455.
8
DNA sequence analysis: a procedure to find homologies among many sequences.DNA序列分析：一种在众多序列中寻找同源性的程序。
Nucleic Acids Res. 1986 Jan 10;14(1):543-50. doi: 10.1093/nar/14.1.543.
9
IBM microcomputer programs that analyze DNA sequences for tRNA genes.用于分析tRNA基因DNA序列的IBM微型计算机程序。
Comput Appl Biosci. 1986 Apr;2(1):13-7. doi: 10.1093/bioinformatics/2.1.13.
10
SEQIN-ST and CODFREG: a full screen sequence editor and a codon usage analysis program for the Atari ST.SEQIN - ST和CODFREG：一款适用于雅达利ST计算机的全屏序列编辑器和密码子使用分析程序。
Nucleic Acids Res. 1988 Mar 11;16(5):1821-7. doi: 10.1093/nar/16.5.1821.

引用本文的文献

1
Actin genes expressed during early development ofPatella vulgata.在紫贻贝早期发育过程中表达的肌动蛋白基因。
Rouxs Arch Dev Biol. 1993 Mar;202(2):77-84. doi: 10.1007/BF00636532.
2
Microhomology-mediated end joining is the principal mediator of double-strand break repair during mitochondrial DNA lesions.微同源性介导的末端连接是线粒体DNA损伤期间双链断裂修复的主要介质。
Mol Biol Cell. 2016 Jan 15;27(2):223-35. doi: 10.1091/mbc.E15-05-0260. Epub 2015 Nov 25.
3
Genes for tRNA(Asp), tRNA (Pro), tRNA (Tyr) and two tRNAs (Ser) in wheat mitochondrial DNA.小麦线粒体 DNA 中的 tRNA(Asp)、tRNA(Pro)、tRNA(Tyr)和两个 tRNA(Ser)基因。
Plant Mol Biol. 1988 May;10(3):251-62. doi: 10.1007/BF00027402.
4
Multiple sequence rearrangements accompanying the duplication of a tRNA(Pro) gene in wheat mitochondrial DNA.小麦线粒体 DNA 中伴随 tRNA(Pro)基因重复的多次序列重排。
Plant Mol Biol. 1988 Nov;11(6):833-43. doi: 10.1007/BF00019523.
5
Evidence for N- and C-terminal processing of a plant defense-related enzyme: Primary structure of tobacco prepro-beta-1,3-glucanase.植物防御相关酶的 N-和 C-末端加工的证据：烟草 β-1,3-葡聚糖酶前体的一级结构。
Proc Natl Acad Sci U S A. 1988 Aug;85(15):5541-5. doi: 10.1073/pnas.85.15.5541.
6
Regulation of a plant pathogenesis-related enzyme: Inhibition of chitinase and chitinase mRNA accumulation in cultured tobacco tissues by auxin and cytokinin.植物病程相关酶的调节：生长素和细胞分裂素对培养烟草组织中几丁质酶和几丁质酶 mRNA 积累的抑制作用。
Proc Natl Acad Sci U S A. 1987 Jan;84(1):89-93. doi: 10.1073/pnas.84.1.89.
7
Nucleotide sequence of bean golden mosaic virus and a model for gene regulation in geminiviruses.豆科金黄花叶病毒的核苷酸序列及双生病毒基因调控的模式。
Proc Natl Acad Sci U S A. 1985 Jun;82(11):3572-6. doi: 10.1073/pnas.82.11.3572.
8
Multiple spacer sequences in the nuclear large subunit ribosomal RNA gene of Crithidia fasciculata.法菲毛滴虫核大亚基核糖体 RNA 基因中的多个间隔序列。
EMBO J. 1987 Apr;6(4):1063-71. doi: 10.1002/j.1460-2075.1987.tb04859.x.
9
Identification of a putative mitochondrial RNA polymerase from Physarum polycephalum: characterization, expression, purification, and transcription in vitro.多头绒泡菌中一种假定的线粒体RNA聚合酶的鉴定：特性、表达、纯化及体外转录
Curr Genet. 2006 Apr;49(4):259-71. doi: 10.1007/s00294-005-0053-y. Epub 2006 Jan 10.
10
Analysis of intergenic spacer transcripts suggests 'read-around' transcription of the extrachromosomal circular rDNA in Euglena gracilis.基因间间隔转录本分析表明纤细裸藻中染色体外环状rDNA存在“通读”转录。
Nucleic Acids Res. 2001 May 15;29(10):2191-8. doi: 10.1093/nar/29.10.2191.

本文引用的文献

1
Structure, organization and evolution of developmentally regulated chorion genes in a silkmoth.家蚕中发育调控型绒毛膜基因的结构、组织与进化
Cell. 1980 Dec;22(3):855-67. doi: 10.1016/0092-8674(80)90562-0.
2
An interactive graphics program for comparing and aligning nucleic acid and amino acid sequences.一个用于比较和比对核酸及氨基酸序列的交互式图形程序。
Nucleic Acids Res. 1982 May 11;10(9):2951-61. doi: 10.1093/nar/10.9.2951.
3
Two-dimensional graphic analysis of DNA sequence homologies.DNA序列同源性的二维图形分析
Nucleic Acids Res. 1982 Jan 11;10(1):365-74. doi: 10.1093/nar/10.1.365.
4
SEQ: a nucleotide sequence analysis and recombination system.SEQ：一种核苷酸序列分析与重组系统。
Nucleic Acids Res. 1982 Jan 11;10(1):279-94. doi: 10.1093/nar/10.1.279.
5
Incompletely base-paired flip-flop terminal loops link the two DNA strands of the vaccinia virus genome into one uninterrupted polynucleotide chain.不完全碱基配对的翻转末端环将痘苗病毒基因组的两条DNA链连接成一条不间断的多核苷酸链。
Cell. 1982 Feb;28(2):315-24. doi: 10.1016/0092-8674(82)90349-x.
6
Regulation of the S10 ribosomal protein operon in E. coli: nucleotide sequence at the start of the operon.大肠杆菌中S10核糖体蛋白操纵子的调控：操纵子起始处的核苷酸序列
Cell. 1981 Oct;26(2 Pt 2):205-11. doi: 10.1016/0092-8674(81)90303-2.
7
Nucleotide sequence of Escherichia coli trpE. Anthranilate synthetase component I contains no tryptophan residues.大肠杆菌色氨酸E的核苷酸序列。邻氨基苯甲酸合成酶组分I不含色氨酸残基。
J Mol Biol. 1981 Feb 15;146(1):45-54. doi: 10.1016/0022-2836(81)90365-x.
8
Deletions of distal sequence after termination of transcription at the end of the tryptophan operon in E. coli.大肠杆菌色氨酸操纵子末端转录终止后远端序列的缺失。
Cell. 1980 Apr;19(4):829-36. doi: 10.1016/0092-8674(80)90073-2.
9
Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments.克隆的人类和小鼠κ免疫球蛋白恒定区和J区基因在功能片段上保持同源性。
Cell. 1980 Nov;22(1 Pt 1):197-207. doi: 10.1016/0092-8674(80)90168-3.
10
Analysis of a drosophila tRNA gene cluster.果蝇tRNA基因簇的分析。
Cell. 1980 Apr;19(4):889-95. doi: 10.1016/0092-8674(80)90080-x.

一款适用于IBM个人计算机的综合序列分析程序。

A comprehensive sequence analysis program for the IBM personal computer.

作者信息

Queen C, Korn L J

出版信息

Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):581-99. doi: 10.1093/nar/12.1part2.581.

DOI:10.1093/nar/12.1part2.581
PMID:6546431
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC321072/
Abstract

We have developed a versatile program for the analysis of nucleic acid and protein sequences on the IBM Personal Computer. The program is interactive and self-instructing. It contains all the features generally found in sequence analysis programs on large computers, including extensive homology routines, as well as new procedures for the entry of sequence data. The program contains facilities to store and utilize the entire Nucleic Acid Sequence Data Bank. We have devised a new algorithm to find restriction enzyme sites, which allows our microcomputer program to find all sites on a small plasmid for 100 different enzymes in 1 to 2 minutes.

摘要

我们已经开发了一个通用程序，用于在IBM个人计算机上分析核酸和蛋白质序列。该程序具有交互式和自我指导功能。它包含大型计算机上序列分析程序中常见的所有功能，包括广泛的同源性例程，以及用于输入序列数据的新程序。该程序具备存储和利用整个核酸序列数据库的功能。我们设计了一种新算法来查找限制性酶切位点，这使得我们的微型计算机程序能够在1到2分钟内找到小质粒上100种不同酶的所有位点。