人类感染伯氏疏螺旋体与其他蜱传病原体的合并感染：来自波兰的两例病例。

Co-infection with Borrelia species and other tick-borne pathogens in humans: two cases from Poland.

作者信息

Welc-Falęciak Renata, Hildebrandt Anke, Siński Edward

机构信息

Department of Parasitology, Institute of Zoology, University of Warsaw, Warsaw, Poland.

出版信息

Ann Agric Environ Med. 2010;17(2):309-13.

PMID:21186774

Abstract

Co-infection with Borrelia species and Anaplasma phagocytophilum or Babesia spp. was assessed in a retrospective study of tick-exposed individuals from southeastern Poland. The co-infection rate of these pathogens was found to be rather low (Borrelia spp./Anaplasma phagocytophilum--4.2%, 1/24; Borrelia spp./Babesia spp.--4.2%, 1/24). However, due to the increased prevalence of Borrelia spp. in Ixodes ricinus ticks in Poland and the recent emergence of new tick-borne infections, it is necessary to carefully evaluate the true risk of human infection with several pathogens using more sensitive and reliable diagnostic tools. This is the first report of human infection with Babesia spp. in Poland that has been confirmed by molecular techniques with homology of 98.9% to B. divergens or Babesia EU1.

摘要

在一项针对波兰东南部蜱虫暴露个体的回顾性研究中，评估了伯氏疏螺旋体与嗜吞噬细胞无形体或巴贝斯虫属的共同感染情况。发现这些病原体的共同感染率相当低（伯氏疏螺旋体/嗜吞噬细胞无形体——4.2%，1/24；伯氏疏螺旋体/巴贝斯虫属——4.2%，1/24）。然而，由于波兰蓖麻硬蜱中伯氏疏螺旋体的流行率增加以及最近新出现的蜱传感染，有必要使用更敏感和可靠的诊断工具仔细评估人类感染多种病原体的真实风险。这是波兰首例经分子技术确诊的人类巴贝斯虫属感染报告，与分歧巴贝斯虫或巴贝斯虫EU1的同源性为98.9%。