Miyanishi Keita, Jingushi Seiya, Torisu Takehiko
Department of Orthopaedic Surgery, Kyushu Rosai Hospital, Kitakyushu, Japan.
J Orthop Surg (Hong Kong). 2010 Dec;18(3):265-70. doi: 10.1177/230949901001800301.
To assess factors that influence 4-year mortality following hip fracture surgery in a Japanese population.
Records of 129 hips in 24 men and 103 women aged 50 to 103 (mean, 79) years who underwent surgery for femoral neck or trochanteric fractures were reviewed. Clinical data reviewed included age, gender, body mass index (BMI), side of fracture, fracture type, fracture stability, surgery type, interval from admission to surgery, length of hospital stay, number of pre-fracture comorbidities, pre-fracture ambulatory level, pre-fracture place of residence, preoperative dementia, preoperative skeletal traction, blood haemoglobin level, serum albumin level, number of postoperative complications, and postoperative delirium. Univariate and multiple logistic regression analyses were performed to identify the relative contribution of the variables to mortality. Receiver operating characteristic (ROC) curves were used to identify optimal cut-off levels.
The 4-year mortality was 48%. Multiple logistic regression analysis showed that serum albumin level (p = 0.0004, odds ratio [OR] = 5.8541) and BMI (p = 0.0192, OR = 1.1693) significantly influenced mortality; the cut-off points were 36 g/l and 18.9 kg/m square, respectively, based on the ROC curves. Kaplan-Meier curves showed that survival rates were significantly worse in patients with values below these cut-off points.
Serum albumin level and BMI on admission are predictive of mortality after hip fracture surgery.
评估影响日本人群髋部骨折手术后4年死亡率的因素。
回顾了24名男性和103名女性(年龄50至103岁,平均79岁)因股骨颈或转子间骨折接受手术的129例髋部病例记录。所回顾的临床数据包括年龄、性别、体重指数(BMI)、骨折部位、骨折类型、骨折稳定性、手术类型、入院至手术的间隔时间、住院时间、骨折前合并症数量、骨折前活动水平、骨折前居住地点、术前痴呆、术前骨骼牵引、血红蛋白水平、血清白蛋白水平、术后并发症数量以及术后谵妄。进行单因素和多因素逻辑回归分析以确定这些变量对死亡率的相对影响。采用受试者工作特征(ROC)曲线确定最佳截断水平。
4年死亡率为48%。多因素逻辑回归分析显示,血清白蛋白水平(p = 0.0004,比值比[OR] = 5.8541)和BMI(p = 0.0192,OR = 1.1693)对死亡率有显著影响;根据ROC曲线,截断点分别为36 g/l和18.9 kg/m²。Kaplan-Meier曲线显示,低于这些截断点值的患者生存率显著更差。
入院时的血清白蛋白水平和BMI可预测髋部骨折手术后的死亡率。