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透明质酸:牙周再生的一种有前景的介质。

Hyaluronic acid: a promising mediator for periodontal regeneration.

作者信息

Bansal Jyoti, Kedige Suresh D, Anand Samir

机构信息

Department of Periodontics and Oral Implantology, M.M.University Mullana, Ambala, Haryana, India.

出版信息

Indian J Dent Res. 2010 Oct-Dec;21(4):575-8. doi: 10.4103/0970-9290.74232.

DOI:10.4103/0970-9290.74232
PMID:21187628
Abstract

Hyaluronic acid (HA) is a natural-non sulphated high molecular weight glycosaminoglycan that forms a critical component of the extracellular matrix and contributes significantly to tissue hydrodynamics, cell migration and proliferation. The use of HA in the treatment of inflammatory process is established in medical areas such as orthopedics, dermatology and ophthalmology. In the field of dentistry, hyaluronate has shown anti-inflammatory, antiedematous and anti-bacterial effects for the treatment of gingivitis and periodontitis. Due to its potential role in modulation of wound healing, its administration to periodontal wound sites could achieve comparable beneficial effects in periodontal tissue regeneration and periodontal disease treatment.

摘要

透明质酸(HA)是一种天然的非硫酸化高分子量糖胺聚糖,它是细胞外基质的关键组成部分,对组织流体动力学、细胞迁移和增殖有重要贡献。在骨科、皮肤科和眼科等医学领域,HA已被用于治疗炎症过程。在牙科领域,透明质酸盐已显示出对牙龈炎和牙周炎治疗的抗炎、消肿和抗菌作用。由于其在调节伤口愈合方面的潜在作用,将其应用于牙周伤口部位可在牙周组织再生和牙周疾病治疗中取得类似的有益效果。

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