Kumar Bc Sharath, Gopal Mg, Talwar Ankur, Ramesh M
Department of Dermatology, Kempegowda Institute of Medical Sciences Hospital, Bangalore, India.
Int J Trichology. 2010 Jan;2(1):60-2. doi: 10.4103/0974-7753.66919.
Neurofibroma is a benign tumor of the peripheral nerve sheath characterized by proliferation of Schwann cells, perineural cells and endoneurial fibroblasts. Different types of neurofibromas can be identified, including localized, plexiform, and diffuse types. Diffuse neurofibroma is an uncommon form of neurofibroma that occurs primarily in children and young adults. The head and neck regions are the most common sites of involvement. Diffuse neurofibroma is an ill-defined infiltrative lesion and tends to involve the skin and subcutaneous tissues. It produces localized thickening and induration of the skin. We present a case of a 12-year-old boy who had a diffuse neurofibroma on the scalp since the age of 2 years.
神经纤维瘤是一种周围神经鞘的良性肿瘤,其特征为施万细胞、神经周细胞和神经内膜成纤维细胞的增殖。可以识别出不同类型的神经纤维瘤,包括局限性、丛状和弥漫性类型。弥漫性神经纤维瘤是神经纤维瘤的一种罕见形式,主要发生于儿童和年轻人。头颈部是最常受累的部位。弥漫性神经纤维瘤是一种边界不清的浸润性病变,倾向于累及皮肤和皮下组织。它会导致皮肤局部增厚和硬结。我们报告一例12岁男孩的病例,该男孩自2岁起头皮上就患有弥漫性神经纤维瘤。